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  4. Recombinant Danio rerio ADP-ribosylation factor-like protein 13B (arl13b)

Recombinant Danio rerio ADP-ribosylation factor-like protein 13B (arl13b)

  • 中文名稱：
    Recombinant Danio rerio ADP-ribosylation factor-like protein 13B(arl13b)
  • 貨號(hào)：
    CSB-YP815612DIL
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Danio rerio ADP-ribosylation factor-like protein 13B(arl13b)
  • 貨號(hào)：
    CSB-EP815612DIL
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Danio rerio ADP-ribosylation factor-like protein 13B(arl13b)
  • 貨號(hào)：
    CSB-EP815612DIL-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Danio rerio ADP-ribosylation factor-like protein 13B(arl13b)
  • 貨號(hào)：
    CSB-BP815612DIL
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Danio rerio ADP-ribosylation factor-like protein 13B(arl13b)
  • 貨號(hào)：
    CSB-MP815612DIL
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    arl13b
  • Uniprot No.：
  • 別名：
    arl13b; arl2l1ADP-ribosylation factor-like protein 13B; ADP-ribosylation factor-like protein 2-like 1; ARL2-like protein 1; Protein scorpion
  • 種屬：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-407
  • 氨基酸序列
    MFNLMANCCN WLKRWREPAR KVTLVMVGLD NAGKTATVRG IQGESPLDVA PTVGFSKVDL KQGKFEVTIF DLGGGKRIRG IWKNYYSESY GVVFVVDSSD VQRIQETRDT MAEVLRHPRI AGKPVLVLAN KQDQDGAMAE ADIIETLSLE KLVNENKCLC QIEPCSAVLG YGKKVDKSIK NGLNWLLNNI AKDYEAISER VQKDTAEQKA QEEQDKKERA ERVRRIREER DRQEREEAER EGRTLKEEEL DDVNMFNPFQ PINNVLTENQ DRLNREKEMQ RQRENGQQGS VQEQIALQDE EEEEEDEESE RQTPESTESG AVDQTKKKTR KLRLKRKHRV DPLRMEEAAP KSPTPPPLPV GWATPKVSRL PKLEPLGDTR HSDFYGKPLP PVAIRQRPNS DTHDVIS
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex Required during embryogenesis for cilia formation in multiple organs such as the pronephric duct.
  • 基因功能參考文獻(xiàn)：
    1. Between 2 and 5 days post fertilization (dpf), arl13b is expressed in neural tissues while expression of arl13a is downregulated by 2 dpf and restricted to craniofacial structures. These results indicate that arl13a and arl13b have evolved different roles and that arl13a does not function in the zebrafish retina. PMID: 30009987
    2. loss of Arl13b leads to slow photoreceptor degeneration, but can be exacerbated by the loss of vangl2. Importantly, the data show that Arl13b can genetically and physically interact with Vangl2 and this association is important for normal photoreceptor structure. PMID: 27571019
    3. Arl13b is an important effector of ciliary membrane biogenesis and ciliary length regulation. PMID: 25448689
    4. Cilia localization is essential for in vivo functions of the Joubert syndrome protein arl13b. PMID: 19906870
  • 亞細(xì)胞定位：
    Cell projection, cilium membrane; Lipid-anchor. Note=Associates to the cilium membrane via palmitoylation. Localizes to proximal ciliary membranes, to an inversin-like subciliary membrane compartment, excluding the transition zone.
  • 蛋白家族：
    Small GTPase superfamily, Arf family
  • 組織特異性：
    Cilium-specific.
  • 數(shù)據(jù)庫鏈接：


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