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  4. Recombinant Crotalus atrox Zinc metalloproteinase-disintegrin VAP2B

Recombinant Crotalus atrox Zinc metalloproteinase-disintegrin VAP2B

  • 中文名稱：
    Recombinant Crotalus atrox Zinc metalloproteinase-disintegrin VAP2B
  • 貨號：
    CSB-YP852655DYC
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Crotalus atrox Zinc metalloproteinase-disintegrin VAP2B
  • 貨號：
    CSB-EP852655DYC
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Crotalus atrox Zinc metalloproteinase-disintegrin VAP2B
  • 貨號：
    CSB-EP852655DYC-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Crotalus atrox Zinc metalloproteinase-disintegrin VAP2B
  • 貨號：
    CSB-BP852655DYC
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Crotalus atrox Zinc metalloproteinase-disintegrin VAP2B
  • 貨號：
    CSB-MP852655DYC
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    N/A
  • Uniprot No.：
  • 別名：
    ; Zinc metalloproteinase-disintegrin-like VAP2B; EC 3.4.24.-; Catrocollastatin; Snake venom metalloproteinase; SVMP; Vascular apoptosis-inducing protein 2B; VAP2B) [Cleaved into: Disintegrin-like catrocollastatin-C]
  • 種屬：
    Crotalus atrox (Western diamondback rattlesnake)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    190-609
  • 氨基酸序列
    E HQKYNPFRFV ELFLVVDKAM VTKNNGDLDK IKTRMYEIVN TVNEIYRYMY IHVALVGLEI WSNEDKITVK PEAGYTLNAF GEWRKTDLLT RKKHDNAQLL TAIDLDRVIG LAYVGSMCHP KRSTGIIQDY SEINLVVAVI MAHEMGHNLG INHDSGYCSC GDYACIMRPE ISPEPSTFFS NCSYFECWDF IMNHNPECIL NEPLGTDIIS PPVCGNELLE VGEECDCGTP ENCQNECCDA ATCKLKSGSQ CGHGDCCEQC KFSKSGTECR ASMSECDPAE HCTGQSSECP ADVFHKNGQP CLDNYGYCYN GNCPIMYHQC YDLFGADVYE AEDSCFERNQ KGNYYGYCRK ENGNKIPCAP EDVKCGRLYC KDNSPGQNNP CKMFYSNEDE HKGMVLPGTK CADGKVCSNG HCVDVATAY
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 668
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    zinc metalloprotease that abolishes platelet aggregation induced by collagen, but has no effect on platelet aggregation induced by ADP or thromboxane analog. This inhibition may be due to its ability to bind collagen and block the binding site on collagen for platelets and/or to its ability to bind to the platelet alpha-2/beta-1 collagen receptor (ITGA2/ITGB1) to block its interaction with collagen and hence prevent platelet stimulation.; Disintegrin catrocollastatin-C: abolishes platelet aggregation induced by collagen (IC(50)=66 nM) but not ADP-stimulated platelet aggregation. This inhibition may be due to its ability to bind collagen and block the binding site on collagen for platelets and/or to its ability to bind to the platelet alpha-2/beta-1 collagen receptor (ITGA2/ITGB1) to block its interaction with collagen and hence prevent platelet stimulation.
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Venom metalloproteinase (M12B) family, P-III subfamily, P-IIIb sub-subfamily
  • 組織特異性：
    Expressed by the venom gland.


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