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  4. Recombinant Cricetus cricetus Torsin-1A (TOR1A)

Recombinant Cricetus cricetus Torsin-1A (TOR1A)

  • 中文名稱：
    Recombinant Cricetus cricetus Torsin-1A(TOR1A)
  • 貨號：
    CSB-YP863657CRZ
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Cricetus cricetus Torsin-1A(TOR1A)
  • 貨號：
    CSB-EP863657CRZ
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Cricetus cricetus Torsin-1A(TOR1A)
  • 貨號：
    CSB-EP863657CRZ-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Cricetus cricetus Torsin-1A(TOR1A)
  • 貨號：
    CSB-BP863657CRZ
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Cricetus cricetus Torsin-1A(TOR1A)
  • 貨號：
    CSB-MP863657CRZ
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    TOR1A; DYT1; Torsin-1A; Dystonia 1 protein; Torsin ATPase 1; EC 3.6.4.-; Torsin family 1 member A; Fragment
  • 種屬：
    Cricetus cricetus (Black-bellied hamster)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-273
  • 氨基酸序列
    AECCGQKRSL SREALQKDLD DKLFGQHLAK KVILNAVSGF LSNPKPKKPL TLSLHGWTGT GKNFASKIIA ENIYEGGLNS DYVHLFVATL HFPHASNVTL YKDQLQMWIR GNVSACARSI FIFDEMDKMH AGLIDAIKPF LDYYDVVDEV SYQKAIFIFL SNAGAERITD VALDFWKSGK QREEIKLRDM EHALAVSVFN NKNSGFWHSS LIDRNLIDYF VPFLPLEYKH LKMCIRVEMQ SRGYEVDEDI ISKVAEEMTF FPKEERVFSD KGC
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Protein with chaperone functions important for the control of protein folding, processing, stability and localization as well as for the reduction of misfolded protein aggregates. Involved in the regulation of synaptic vesicle recycling, controls STON2 protein stability in collaboration with the COP9 signalosome complex (CSN). In the nucleus, may link the cytoskeleton with the nuclear envelope, this mechanism seems to be crucial for the control of nuclear polarity, cell movement and, specifically in neurons, nuclear envelope integrity. Participates in the cellular trafficking and may regulate the subcellular location of multipass membrane proteins such as the dopamine transporter SLC6A3, leading to the modulation of dopamine neurotransmission. In the endoplasmic reticulum, plays a role in the quality control of protein folding by increasing clearance of misfolded proteins such as SGCE variants or holding them in an intermediate state for proper refolding. May have a redundant function with TOR1B in non-neural tissues.
  • 亞細(xì)胞定位：
    Endoplasmic reticulum lumen. Nucleus membrane; Peripheral membrane protein. Cell projection, growth cone. Cytoplasmic vesicle membrane. Cell junction, synapse, synaptosome. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    ClpA/ClpB family, Torsin subfamily


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