在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Chlorocebus aethiops DNA damage-binding protein 1 (DDB1), partial

Recombinant Chlorocebus aethiops DNA damage-binding protein 1 (DDB1), partial

  • 中文名稱：
    Recombinant Chlorocebus aethiops DNA damage-binding protein 1(DDB1) ,partial
  • 貨號：
    CSB-YP006581DSU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Chlorocebus aethiops DNA damage-binding protein 1(DDB1) ,partial
  • 貨號：
    CSB-EP006581DSU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Chlorocebus aethiops DNA damage-binding protein 1(DDB1) ,partial
  • 貨號：
    CSB-EP006581DSU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Chlorocebus aethiops DNA damage-binding protein 1(DDB1) ,partial
  • 貨號：
    CSB-BP006581DSU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Chlorocebus aethiops DNA damage-binding protein 1(DDB1) ,partial
  • 貨號：
    CSB-MP006581DSU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    DDB1DNA damage-binding protein 1; DDB p127 subunit; DDBa; Damage-specific DNA-binding protein 1; UV-damaged DNA-binding protein 1; UV-DDB 1
  • 種屬：
    Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Protein, which is both involved in DNA repair and protein ubiquitination, as part of the UV-DDB complex and DCX (DDB1-CUL4-X-box) complexes, respectively. Core component of the UV-DDB complex (UV-damaged DNA-binding protein complex), a complex that recognizes UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4 photoproducts (6-4 PP), apurinic sites and short mismatches. Also functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the DCX E3 ubiquitin-protein ligase complex is determined by the variable substrate recognition component recruited by DDB1. DCX(DDB2) (also known as DDB1-CUL4-ROC1, CUL4-DDB-ROC1 and CUL4-DDB-RBX1) may ubiquitinate histone H2A, histone H3 and histone H4 at sites of UV-induced DNA damage. The ubiquitination of histones may facilitate their removal from the nucleosome and promote subsequent DNA repair. DCX(DDB2) also ubiquitinates XPC, which may enhance DNA-binding by XPC and promote NER. DCX(DTL) plays a role in PCNA-dependent polyubiquitination of CDT1 and MDM2-dependent ubiquitination of TP53 in response to radiation-induced DNA damage and during DNA replication. DCX(ERCC8) (the CSA complex) plays a role in transcription-coupled repair (TCR). The DDB1-CUL4A-DTL E3 ligase complex regulates the circadian clock function by mediating the ubiquitination and degradation of CRY1. DDB1-mediated CRY1 degradation promotes FOXO1 protein stability and FOXO1-mediated gluconeogenesis in the liver.
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    DDB1 family


主站蜘蛛池模板： 伊人久久大香线蕉综合75| 国产超碰无码最新上传| 在线看片免费人成视频在线影院| 国产亚洲人成网站在线观看| 国产精品久久久久久久久久久久人四虎 | 强被迫伦姧惨叫人妻系列| 野外被强j到高潮免费观看| 精品免费国产一区二区三区四区介绍| 国产a在亚洲线播放| 日韩精品中文字幕无码专区| 国内一区二区三区香蕉aⅴ| 性饥渴少妇av无码毛片| 日韩精品久久无码中文字幕| 很色很爽很黄裸乳视频| 亚洲欧美综合精品成人导航| 日本熟妇乱子伦xxxx| 中文成人在线| 欧美亚洲国产精品久久蜜芽| 乱子伦农村xxxxbbb| 成年午夜无码av片在线观看| 精品少妇ay一区二区三区| 无翼乌工口全彩肉肉无遮挡18| 欧美日韩无砖专区一中文字| 久久国产中文娱乐网| 欧美不卡高清一区二区三区| 中文字幕一区二区精品区| 在线观看无码av免费不卡软件| 搡8o老女人老妇人老熟| 欧美又粗又大又硬又长又爽视频| 一区二区三区毛aaaa片特级| 麻豆一区二区在我观看| 免费国产a国产片高清| 亚洲欧美成人片在线观看| 蜜臀av色欲a片无码一区二区| 国产情侣久久久久aⅴ免费| 国产成人欧美亚洲日韩电影| 亚洲日韩中文字幕在线不卡最新| 情侣做性视频在线播放| 8av国产精品爽爽ⅴa在线观看| 一本色道久久综合狠狠躁篇| 欧美大屁股熟妇bbbbbb|