在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Chlorocebus aethiops DNA damage-binding protein 1 (DDB1), partial

Recombinant Chlorocebus aethiops DNA damage-binding protein 1 (DDB1), partial

  • 中文名稱：
    Recombinant Chlorocebus aethiops DNA damage-binding protein 1(DDB1) ,partial
  • 貨號：
    CSB-YP006581DSU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Chlorocebus aethiops DNA damage-binding protein 1(DDB1) ,partial
  • 貨號：
    CSB-EP006581DSU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Chlorocebus aethiops DNA damage-binding protein 1(DDB1) ,partial
  • 貨號：
    CSB-EP006581DSU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Chlorocebus aethiops DNA damage-binding protein 1(DDB1) ,partial
  • 貨號：
    CSB-BP006581DSU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Chlorocebus aethiops DNA damage-binding protein 1(DDB1) ,partial
  • 貨號：
    CSB-MP006581DSU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    DDB1DNA damage-binding protein 1; DDB p127 subunit; DDBa; Damage-specific DNA-binding protein 1; UV-damaged DNA-binding protein 1; UV-DDB 1
  • 種屬：
    Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Protein, which is both involved in DNA repair and protein ubiquitination, as part of the UV-DDB complex and DCX (DDB1-CUL4-X-box) complexes, respectively. Core component of the UV-DDB complex (UV-damaged DNA-binding protein complex), a complex that recognizes UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4 photoproducts (6-4 PP), apurinic sites and short mismatches. Also functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the DCX E3 ubiquitin-protein ligase complex is determined by the variable substrate recognition component recruited by DDB1. DCX(DDB2) (also known as DDB1-CUL4-ROC1, CUL4-DDB-ROC1 and CUL4-DDB-RBX1) may ubiquitinate histone H2A, histone H3 and histone H4 at sites of UV-induced DNA damage. The ubiquitination of histones may facilitate their removal from the nucleosome and promote subsequent DNA repair. DCX(DDB2) also ubiquitinates XPC, which may enhance DNA-binding by XPC and promote NER. DCX(DTL) plays a role in PCNA-dependent polyubiquitination of CDT1 and MDM2-dependent ubiquitination of TP53 in response to radiation-induced DNA damage and during DNA replication. DCX(ERCC8) (the CSA complex) plays a role in transcription-coupled repair (TCR). The DDB1-CUL4A-DTL E3 ligase complex regulates the circadian clock function by mediating the ubiquitination and degradation of CRY1. DDB1-mediated CRY1 degradation promotes FOXO1 protein stability and FOXO1-mediated gluconeogenesis in the liver.
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    DDB1 family


主站蜘蛛池模板： 精品国产福利一区二区| 强奷人妻日本中文字幕| 色欲欲www成人网站| 亚洲国产99精品国自产拍| 国产精品久久国产精麻豆99网站| 国产肉体xxxx裸体784大胆| 国产麻豆精品一区| 国产有奶水哺乳期无码avav| 国产成人片无码免费视频软件 | 国产白嫩护士被弄高潮| 疯狂做受xxxx高潮视频免费| 欲色影视天天一区二区三区色香欲| 亚洲成av人无码中文字幕| 狠狠色狠狠色综合日日五| 人妻无码久久精品| 一边捏奶头一边啪高潮视频| 让少妇高潮无乱码高清在线观看 | 狠狠躁夜夜躁人人躁婷婷| 99re久久热在这里精品| 无码孕妇孕交在线观看| 国产97在线 | 免费| 欧美性色黄大片www喷水| 国产精品av一区二区三区不卡蜜| 99久久亚洲精品无码毛片| 国产激情久久久久影院老熟女免费 | 级r片内射在线视频播放| 麻豆国产在线精品国偷产拍| 国产亚洲精品久久久久久禁果tv| 亚洲熟妇少妇任你躁在线观看无码| 国产免费一区二区三区免费视频| 国产日产欧产精品精品app| 国产国拍精品av在线观看按摩| 女人大荫蒂毛茸茸视频| 人妻中文字幕无码系列| 亚洲自偷自拍另类小说| 日本夜爽爽一区二区三区| 久久亚洲精品ab无码播放| 国产亚洲曝欧美曝妖精品| 亚洲国产果冻传媒av在线观看| 亚洲综合无码一区二区| 久久精品成人无码观看不卡|