在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Chicken anemia virus Dual specificity protein phosphatase VP2 (VP2)

Recombinant Chicken anemia virus Dual specificity protein phosphatase VP2 (VP2)

  • 中文名稱：
    Recombinant Chicken anemia virus Dual specificity protein phosphatase VP2(VP2)
  • 貨號：
    CSB-YP302471CID
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Chicken anemia virus Dual specificity protein phosphatase VP2(VP2)
  • 貨號：
    CSB-EP302471CID
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Chicken anemia virus Dual specificity protein phosphatase VP2(VP2)
  • 貨號：
    CSB-EP302471CID-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Chicken anemia virus Dual specificity protein phosphatase VP2(VP2)
  • 貨號：
    CSB-BP302471CID
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Chicken anemia virus Dual specificity protein phosphatase VP2(VP2)
  • 貨號：
    CSB-MP302471CID
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    VP2
  • Uniprot No.：
  • 別名：
    VP2Dual specificity protein phosphatase VP2; EC 3.1.3.16; EC 3.1.3.48
  • 種屬：
    Chicken anemia virus (isolate Germany Cuxhaven-1) (CAV)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-216
  • 氨基酸序列
    MHGNGGQPAA GGSESALSRE GQPGPSGAAQ GQVISNERSP RRYSTRTING VQATNKFTAV GNPSLQRDPD WYRWNYNHSI AVWLRECSRS HAKICNCGQF RKHWFQECAG LEDRSTQASL EEAILRPLRV QGKRAKRKLD YHYSQPTPNR KKVYKTVRWQ DELADREADF TPSEEDGGTT SSDFDEDINF DIGGDSGIVD ELLGRPFTTP APVRIV
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    May act as a scaffold protein in virion assembly. May also play a role in intracellular signaling during viral replication.
  • 基因功能參考文獻：
    1. The deletion of the C-terminal region of apoptin also impaired the replication of chicken anemia virus and attenuated its virulence in chickens. PMID: 28222746
    2. this study reports the use of apoptin and poly (I:C) combination as a novel strategy for cancer immunotherapy PMID: 27064544
    3. VP3-induced apoptosis, caspase-dependent intrinsic pathway plays an important role with the cleavage of poly (ADP-ribose) polymerase (PARP) PMID: 25809990
    4. Results show that The apoptosis induced by human adenovirus serotype 5 (AdHu5)-apoptin was independent of anti-apoptotic Bcl-2 and Bcl-xL proteins and the p53 pathway. PMID: 23812727
    5. In silico three-dimensional modeling of apoptin, molecular docking experiments between apoptin model and the known structure of Bcr-Abl, and the 3D structures of SH2 domains of CrkL and Bcr-Abl, were performed. PMID: 22253690
    6. These data demonstrate that Hsc70 is responsible for the down-regulation of Apoptin induced RelA/p65 gene expression. PMID: 21707973
    7. Apoptin induced the translocation of endogenous Hsc70 from the cytoplasm to the nucleus, and both were co-localized in the nucleus. PMID: 21565169
    8. Apoptin, expressed from the pseudotype baculovirus vector, has the potential to become a therapeutic agent for the treatment of solid tumors PMID: 19824041
    9. Apoptin, a protein from chicken anemia virus without an apparent cellular homologue, can induce apoptosis in mammalian cells. Its cytotoxicity is limited to transformed or tumor cells. PMID: 14765135
    10. Apoptin induces chromatin condensation when it is expressed in the nucleus and in the cytoplasm. PMID: 15965608
    11. role of c-Jun N-terminal kinase (JNK) in the apoptosis induced by apoptin gene in human lymphoma cell U937 PMID: 15989809
    12. Apoptin expression caused an increase in the tumor suppressor lipid ceramide, which regulates the cellular stress response PMID: 16887394
    13. apoptin kills tumor cells independently of PML and sumoylation, however, the interaction of apoptin with PML and small ubiquitin-like modifier (SUMO) proteins might be relevant for chicken anemia virus replication PMID: 16924230
    14. suggest that apoptin modulates ceramide/sphingolipid metabolism as part of its mechanism of action PMID: 16926120
    15. apoptin had an anti-neoplastic effect in vivo and in vitro in RSV-induced tumours PMID: 16963752
    16. T108 phosphorylation may only be required for the apoptotic activity mediated through the C-terminal apoptosis domain. PMID: 17223075
    17. PI3-K/Akt pathways have a dual role in both survival and cell death processes depending on the stimulus. PMID: 18021174
    18. Human peptidyl-prolyl isomerase-like 3 (Ppil3) is one of the Apoptin-associated proteins. PMID: 18474220
    19. C-terminus of apoptin (residues 74-121) is sufficient for tumor cell-enhanced nuclear targeting through phosphoinhibition of apoptin (74-121)-mediated nuclear export occurring exclusively in tumor cells. PMID: 18798550
    20. apoptin is necessary not only for DNA replication but also virus-like particle production of chicken anemia virus PMID: 19091368
    21. the pathway of apoptin-induced apoptosis and show that it essentially depends on abnormal phosphatidylinositol 3-kinase (PI3-kinase)/Akt activation, resulting in the activation of the cyclin-dependent kinase CDK2 PMID: 19103742
    22. Apoptin specifically kills tumor cells while leaving normal cells unharmed. The subcellular localization of apoptin appears to be crucial for this tumor-selective activity. Review. PMID: 19374922

    顯示更多

    收起更多

  • 蛋白家族：
    Gyrovirus protein VP2 family


主站蜘蛛池模板： 国产日韩一区二区三免费高清| 久热爱精品视频线路一| 加勒比东京热无码一区| 少妇人妻精品一区二区三区| 久久婷婷五月综合色精品| 日本国产网曝视频在线观看| 无码一卡二卡三卡四卡| 女人喷潮完整视频| 国产97在线 | 免费| 六月丁香综合在线视频| 久久天天躁夜夜躁狠狠躁| 波多野结衣一区二区三区av高清| 夜爽8888视频在线观看| 亚洲中文字幕av不卡无码| 国产v在线最新观看视频| 亚洲人成电影网站色www| 都市激情 在线 亚洲 国产| 国产午夜a理论毛片| 国产成人愉拍精品| 女厕偷窥一区二区三区| 国产乱码日产精品bd| 18禁无遮挡无码国产免费网站| 一区二区三区内射美女毛片| 亚洲熟妇无码乱子av电影| 又爽又色禁片1000视频免费看| 伊人久久大香线蕉影院| 欧美人妻aⅴ中文字幕 | 噜噜噜亚洲色成人网站∨| 亚洲午夜性猛春交xxxx| 天干天干夜啦天干天干国产| 国产精品嫩草影院入口一二三| 亚洲 欧美日韩 综合 国产| 国产亚洲综合网曝门系列 | 秋霞在线观看秋| 永久黄网站免费视频性色| 久久中文精品无码中文字幕下载 | 白嫩无码人妻丰满熟妇啪啪区百度 | 国产中文字字幕乱码无限| www亚洲精品久久久乳| 国产果冻豆传媒麻婆精东| 久久av无码αv高潮αv喷吹|