在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Chicken Vinculin (VCL), partial

Recombinant Chicken Vinculin (VCL), partial

  • 中文名稱：
    雞VCL重組蛋白
  • 貨號：
    CSB-YP025812CH
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    雞VCL重組蛋白
  • 貨號：
    CSB-EP025812CH
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    雞VCL重組蛋白
  • 貨號：
    CSB-EP025812CH-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    雞VCL重組蛋白
  • 貨號：
    CSB-BP025812CH
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    雞VCL重組蛋白
  • 貨號：
    CSB-MP025812CH
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    VCL; VINC1; Vinculin; Metavinculin
  • 種屬：
    Gallus gallus (Chicken)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
  • 基因功能參考文獻：
    1. VASP phosphorylation at Ser(157) mediates its localization at the membrane, but that VASP Ser(157) phosphorylation and membrane localization are not sufficient to activate its actin catalytic activity PMID: 25759389
    2. The importance of the actin-binding site in vinculin, which provide the molecular basis for elucidating additional roles of this interaction, including actin-induced conformational changes that promote actin bundling. PMID: 24685146
    3. Data show that alphaE-catenin D3 binds strongly to vinculin, whereas larger fragments and full-length alphaE-catenin bind approximately 1,000-fold more weakly. PMID: 22586082
    4. The vinculin C-terminal hairpin mediates F-actin bundle formation, focal adhesion, and cell mechanical properties. PMID: 22052910
    5. ACh stimulation regulates vinculin activation in tracheal smooth muscle via RhoA; vinculin activation facilitates connections between actin filaments and talin-integrin adhesion complexes and mediates the initiation of actin polymerization PMID: 21071443
    6. crystal structure: conformational changes in the head, tail and proline-rich domains are linked structurally and thermodynamically; and a combinatorial pathway to activation ensures that vinculin is activated only at sites of cell adhesion PMID: 15195105
    7. A double vinculin mutant protein Y100F/Y1065F localized to focal adhesion plaques. PMID: 15229287
    8. binding to F-actin potentiates a local rearrangement in the vinculin tail that in turn promotes vinculin dimerization and, hence, formation of actin bundles PMID: 16427016
    9. Results show that the interaction between two species with weak affinity in solution, such as vinculin and alpha-actinin, can be visualized in a membrane-like environment. PMID: 16430917
    10. role of pH on vinculin tail domain structure and self-association PMID: 18980387
    11. Lipid binding to the tail domain of vinculin: specificity and the role of the N and C termini PMID: 19110481
    12. vinculin can link adhesion plaques to the cytoskeleton by initiating the formation of bundled actin filaments or by remodeling existing filaments PMID: 19736312

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, adherens junction. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    Vinculin/alpha-catenin family
  • 組織特異性：
    Isoform Metavinculin is muscle-specific.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 伊人色综合久久天天小片| 日本欧美视频在线观看| 无码毛片视频一区二区本码| 色噜噜av亚洲色一区二区| 国产精品美女www爽爽爽视频| 2018亚洲а∨天堂| 久久综合国产乱子伦精品免费| 国产无遮挡又黄又爽在线观看| 精品国产a∨无码一区二区三区| 国产高清japanese在线播放e| 99久视频只有精品2019| 日韩精品亚洲人成在线观看| 亚洲精品美女久久7777777| 天堂mv在线mv免费mv香蕉| 国产亚洲精品久久久ai换脸| 亚洲愉拍99热成人精品热久久| 99精品偷自拍| 亚洲aⅴ无码专区在线观看| 亚洲国产精品自在拍在线播放蜜臀 | av怡红院一区二区三区| 情欲少妇人妻100篇| 怀孕挺大肚子疯狂高潮av毛片| 亚洲熟妇无码av不卡在线播放| 国产激情з∠视频一区二区 | 国产人妖视频一区二区| 香蕉人妻av久久久久天天| 国产亚洲综合欧美视频| 久久综合九色综合国产| 国产精品原创巨作av| 国产精品人成视频国模| 蜜臀av片在线观看| 女人另类牲交zozozo| 性按摩xxxx在线观看| 亚洲精品色播一区二区| 五十路丰满中年熟女中出| 亚洲成a人v影院色老汉影院| 女同亚洲一区二区无线码| 久久影院午夜伦手机不四虎卡| 国内最真实的xxxx人伦| 粉嫩粉嫩的18在线观看| 男女啪啦猛视频免费|