在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Chicken Villin-1 (VIL1), partial

  • 中文名稱:
    雞VIL1重組蛋白
  • 貨號(hào):
    CSB-YP025855CH
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱:
    雞VIL1重組蛋白
  • 貨號(hào):
    CSB-EP025855CH
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱:
    雞VIL1重組蛋白
  • 貨號(hào):
    CSB-EP025855CH-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    雞VIL1重組蛋白
  • 貨號(hào):
    CSB-BP025855CH
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱:
    雞VIL1重組蛋白
  • 貨號(hào):
    CSB-MP025855CH
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    VIL1
  • Uniprot No.:
  • 別名:
    VIL1; VIL; Villin-1
  • 種屬:
    Gallus gallus (Chicken)
  • 蛋白長(zhǎng)度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Epithelial cell-specific Ca(2+)-regulated actin-modifying protein that modulates the reorganization of microvillar actin filaments. Plays a role in the actin nucleation, actin filament bundle assembly, actin filament capping and severing. Binds phosphatidylinositol 4,5-bisphosphate (PIP2) and lysophosphatidic acid (LPA); binds LPA with higher affinity than PIP2. Binding to LPA increases its phosphorylation by SRC and inhibits all actin-modifying activities. Binding to PIP2 inhibits actin-capping and -severing activities but enhances actin-bundling activity. Regulates the intestinal epithelial cell morphology, cell invasion, cell migration and apoptosis. Protects against apoptosis induced by dextran sodium sulfate (DSS) in the gastrointestinal epithelium. Appears to regulate cell death by maintaining mitochondrial integrity. Enhances hepatocyte growth factor (HGF)-induced epithelial cell motility, chemotaxis and wound repair. Its actin-bundling activity is inhibited by tropomyosin.
  • 基因功能參考文獻(xiàn):
    1. The thermostable 36-residue subdomain of the villin headpiece (HP36) is the smallest known cooperatively folding protein. The side chain methyl dynamics of villin HP36 has been measured across a wide range of temperatures. PMID: 26473993
    2. A compact native 24-residues-long supersecondary structure derived from the hyperstable villin headpiece subdomain consisting of helices 2 and 3, is described. PMID: 25650934
    3. side-chain dynamics of several key hydrophobic methyl groups in chicken villin headpiece subdomain (HP36) PMID: 22085262
    4. a buried salt bridge is essential for villin headpiece folding and actin binding PMID: 21449557
    5. detailed comparison of these crystal structures with each other and to our previously determined NMR structures of HP67 PMID: 16142894
    6. Results indicate that reduced conformational flexibility of the N-terminal subdomain in wild-type villin HP67 is due to intramolecular interactions with the His41 imidazole ring. PMID: 16332376
    7. Results presented here demonstrate that unfolding of the villin headpiece is a multistate process. PMID: 16337228
    8. a crucial role for this proline residue in structural stability and folding potential of HP (sub)domains consistent with Pro-Trp stacking as a more general determinant of protein stability PMID: 16697408
    9. Villin headpiece domain HP67 & its mutant (H41Y) are resolved in different crystal form & space groups. 2 molecules occur in each asymmetric unit in the new space group P6(1) differing in harmonic motions. PMID: 19390152

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm, cytoskeleton. Cell projection, microvillus. Cell projection, lamellipodium. Cell projection, ruffle. Cell projection, filopodium tip. Cell projection, filopodium.
  • 蛋白家族:
    Villin/gelsolin family
  • 組織特異性:
    Specifically expressed in epithelial cells. Component of brush border microvilli.
  • 數(shù)據(jù)庫(kù)鏈接:


主站蜘蛛池模板: 久久精品动漫一区二区三区| 大学生久久香蕉国产线看观看| 国产婷婷成人久久av免费高清| 少妇午夜啪爽嗷嗷叫视频| 亚洲中文字幕av不卡无码| 伊人久久大香线蕉aⅴ色| 国产老熟女狂叫对白| 天堂中文在线www天堂在线| 少妇被躁爽到高潮无码久久| 人人做人人爽人人爱| 欧美大屁股流白浆xxxx| 亚洲国产成av人天堂无码| 亚洲午夜成人精品无码| 国产一区二区三区无码免费| 国产在线精品视频免费观看| 99视频精品全部免费 在线| 色一情一乱一伦一区二区三区小说| 无码中文字幕va精品影院| 香蕉97超级碰碰碰视频| 国产私人尤物无码不卡| 少妇无码一区二区二三区| 国产精品久人妻精品| 日韩av无码一区二区三区不卡毛片| 国产精品久久久久久不卡盗摄| 好吊妞国产欧美日韩免费观看| 色哟哟国产精品免费观看| 在线成人a毛片免费播放| 国产成 人 综合 亚洲网站| 亚洲愉拍自拍另类图片| 国产奶头好大揉着好爽视频 | 久久精品国产只有精品96| 国产精品午夜小视频观看| 国产成人精品一区二三区在线观看| 久久久中文字幕日本无吗| 亚洲精品偷拍无码不卡av| 精品美女国产互换人妻| 青青草原综合久久大伊人精品| 香港三日本8a三级少妇三级99 | 麻豆成人久久精品综合网址| 欧美日韩在线视频一区| 狠狠精品干练久久久无码中文字幕|