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  4. Recombinant Chicken T-box transcription factor TBX5 (TBX5), partial

Recombinant Chicken T-box transcription factor TBX5 (TBX5), partial

  • 中文名稱：
    雞TBX5重組蛋白
  • 貨號：
    CSB-YP882497CH
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    雞TBX5重組蛋白
  • 貨號：
    CSB-EP882497CH
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    雞TBX5重組蛋白
  • 貨號：
    CSB-EP882497CH-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    雞TBX5重組蛋白
  • 貨號：
    CSB-BP882497CH
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    雞TBX5重組蛋白
  • 貨號：
    CSB-MP882497CH
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    TBX5; T-box transcription factor TBX5; T-box protein 5
  • 種屬：
    Gallus gallus (Chicken)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    DNA-binding protein that regulates the transcription of several genes and is involved in heart development and limb pattern formation. May bind to the core DNA motif of promoters.
  • 基因功能參考文獻：
    1. Tbx5 and Tbx4 expression in forelimb and hindlimb, respectively, are not sufficient for limb outgrowth and that input from RA is required. PMID: 26212321
    2. Forelimb-restricted expression of Tbx5 and ultimately forelimb formation is therefore achieved through co-option of two characteristics of Hox genes; their colinear expression along the body axis and the functional specificity of different paralogs. PMID: 24651482
    3. Pax6 together with cVax and Tbx5 mediates dorsoventral patterning of the eye PMID: 15322073
    4. LMP4 acts as a repressor of Tbx5 activity. PMID: 16880269
    5. These studies provide in vivo significance of the LMP4/Tbx5 protein interaction, suggesting both nuclear and cytoplasmic roles for Tbx5. PMID: 17045582
    6. An evoluionarily conserved nuclear export signal faciltates localization of the Tbx5 transcription factor. PMID: 18160705
    7. Results show that in the chick retina the compartmentalized expression of retinoic acid metabolizing enzymes RALDH-1, RALDH-3 and CYP26A1 requires the spatially restricted expression of the transcription factors cVax/Vax2 and Tbx5 PMID: 18406560

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  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 數(shù)據(jù)庫鏈接：

    KEGG: gga:373988

    STRING: 9031.ENSGALP00000013419

    UniGene: Gga.961



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