在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Chicken Insulin-like growth factor I (IGF1)

  • 中文名稱:
    Recombinant Chicken Insulin-like growth factor I (IGF1)
  • 貨號:
    CSB-EP011086CH
  • 規(guī)格:
    ¥2340
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 95% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
  • Uniprot No.:
  • 別名:
    IGF-I;Somatomedin
  • 種屬:
    Gallus gallus (Chicken)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    7.9 kDa
  • 表達(dá)區(qū)域:
    49-118aa
  • 氨基酸序列
    GPETLCGAELVDALQFVCGDRGFYFSKPTGYGSSSRRLHHKGIVDECCFQSCDLRRLEMYCAPIKPPKSA
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    Tag-Free
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling.
  • 基因功能參考文獻(xiàn):
    1. It is a protein synthesis-related factor. PMID: 28594135
    2. The coding region of the IGF1 gene was polymorphic, expressed differentially during the pre-hatch and post-hatch periods, and haplogroups showed significant association with growth traits in chicken. PMID: 26059224
    3. The IGF-I gene is significantly associated with some growth traits (body weight at hatching, and at 4, 8, 12, and 14 weeks of age) in chickens. PMID: 23546986
    4. IGF1 single-nucleotide polymorphism c.47673G > A was associated with body weight and haematocrit percentage, and also with feed intake and percentages of abdominal fat and gizzard genotype x sex interactions. PMID: 23275255
    5. Insulin-like growth factor 1 stimulates Non-astrocytic Inner Retinal Glial cells to proliferate, migrate distally into the retina, and become reactive. PMID: 22973454
    6. The objective of this study was to examine associations of an IGF1 promoter polymorphism with growth, body composition, skeleton integrity, and metabolic traits in chickens. PMID: 15742956
    7. Genetic/nutritional models show a positive relation between muscle IGF-1 mRNA levels, which determine paracrine IGF-1 levels, and post hatch muscle growth. (Review) PMID: 16077194
    8. These results suggest that the mechanism of action whereby IGFBP2 excess impairs long bone development is to inhibit IGF-I and IGF-II mediated proliferation and matrix synthesis. PMID: 16183342
    9. Polymorphisms within the IGF1 gene are associated with 5-week body weight. PMID: 16734694
    10. Blood levels ofIGF-I may be more important than IGF-II after chicken hatching PMID: 17369538
    11. Data show that transcription level of IGF-1 decreased dramatically in the sex-linked dwarf. PMID: 17681929
    12. Association analysis showed that haplotypes based on three cIGF1 polymorphisms (c.-366A>C, c.528G>A and c.*1024C>T) were associated with body weight traits, suggesting that cIGF1 or a tightly linked gene had effects on body weight in the chicken. PMID: 18717967
    13. IGF-1 genes and proteins are expressed at high or moderately high levels in healing tendon PMID: 19084187

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    Insulin family
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 久久精品国产99久久丝袜蜜桃| 精品国产一区二区av麻豆不卡| 国产亚洲精品自在久久| 日本japanese漂亮丰满| 亚洲中文字幕无码天然素人| 国产区精品系列在线观看| 亚洲狠狠婷婷综合久久蜜芽| 男人猛吃奶女人爽视频| 在线a亚洲v天堂网2018| 亚洲精品无码久久毛片波多野吉衣| 乱中年女人伦| 粉嫩小泬无遮挡久久久久久| 日韩一区二区三免费高清| 成年网站未满十八禁视频天堂| 四虎国产精品亚洲一区久久特色| 日韩毛片在线视频x| 亚洲色欲色欲www在线丝| 国产精品久久久久久不卡盗摄 | 日本又黄又潮娇喘视频| 夜夜爽夜夜叫夜夜高潮漏水 | 狠狠躁天天躁无码中文字幕| 少妇无码精油按摩专区| 中国内射xxxx6981少妇| 日日av色欲香天天综合网| 色偷一区国产精品| 亚洲成在人线视av| 亚洲精品少妇30p| 99久久精品国产第一页| 国产在线视频主播区| 18禁止午夜福利体验区| 欧美成 人影片 aⅴ免费观看| 丝袜高跟麻麻浓精受孕人妻| 日韩人妻无码精品无码中文字幕| 俄罗斯丰满熟妇hd| 欧美精品免费观看二区| 久久99九九精品久久久久蜜桃 | 国产精品欧美久久久久无广告| 国产成人av区一区二区三| 偷窥 亚洲 另类 图片 熟女| 亚洲一区波多野结衣在线| 亚洲欧洲日产最新|