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  4. Recombinant Chicken Cadherin-6 (CDH6), partial

Recombinant Chicken Cadherin-6 (CDH6), partial

  • 中文名稱：
    Recombinant Chicken Cadherin-6(CDH6) ,partial
  • 貨號：
    CSB-YP845868CH
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Chicken Cadherin-6(CDH6) ,partial
  • 貨號：
    CSB-EP845868CH
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Chicken Cadherin-6(CDH6) ,partial
  • 貨號：
    CSB-EP845868CH-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Chicken Cadherin-6(CDH6) ,partial
  • 貨號：
    CSB-BP845868CH
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Chicken Cadherin-6(CDH6) ,partial
  • 貨號：
    CSB-MP845868CH
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    CDH6; Cadherin-6; Cadherin-6B; c-cad6B
  • 種屬：
    Gallus gallus (Chicken)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
  • 基因功能參考文獻：
    1. Cad6B C-terminal fragments possesses a novel pro-epithelial-to-mesenchymal transition (EMT) role by up-regulating EMT effector genes in vivo. PMID: 27856599
    2. Cad6B is removed from premigratory neural crest cells through cell surface internalization events that include clathrin-mediated endocytosis and macropinocytosis. PMID: 25795298
    3. A dual mechanism for Cad6B proteolysis involving two ADAMs, along with gamma-secretase, during cranial neural crest cell epithelial-to-mesenchymal transitions. PMID: 24196837
    4. the de-epithelialization step of the neural crest epithelial mesenchymal transition by cadherin-6B involves regulation of actin dynamics via LIMK/cofilin PMID: 22537493
    5. find that cadherin 6B persists in early migrating neural crest cells and is required for their emigration from the neural tube. PMID: 20610481
    6. Expression of cadherin 6B at the synaptic level on the somata and the proximal neurites of identified neuron populations has been traced selectively in the developing chicken visual system. PMID: 15312902
    7. Cadherin6B is a direct target of Snail2 repression in vivo and in the context of the EMT that characterizes neural crest development. PMID: 17344227
    8. cadherin-6B was expressed in many song nuclei of the juvenile and adult brain. PMID: 18322922

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  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 數(shù)據(jù)庫鏈接：

    KEGG: gga:414842

    STRING: 9031.ENSGALP00000030382

    UniGene: Gga.600



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