在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Chicken B-cell linker protein (BLNK), partial

Recombinant Chicken B-cell linker protein (BLNK), partial

  • 中文名稱：
    Recombinant Chicken B-cell linker protein(BLNK) ,partial
  • 貨號(hào)：
    CSB-YP896856CH
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Chicken B-cell linker protein(BLNK) ,partial
  • 貨號(hào)：
    CSB-EP896856CH
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Chicken B-cell linker protein(BLNK) ,partial
  • 貨號(hào)：
    CSB-EP896856CH-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Chicken B-cell linker protein(BLNK) ,partial
  • 貨號(hào)：
    CSB-BP896856CH
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Chicken B-cell linker protein(BLNK) ,partial
  • 貨號(hào)：
    CSB-MP896856CH
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    BLNK; BASHB-cell linker protein; B-cell adapter SH2 domain-containing protein; Cytoplasmic adapter protein; Src homology 2 domain-containing leukocyte protein of 65 kDa; SLP-65
  • 種屬：
    Gallus gallus (Chicken)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition. Plays a critical role in B-cell development in the bursa. Plays an important role in BCR-induced apoptosis.
  • 基因功能參考文獻(xiàn)：
    1. In hydrogen peroxide-stimulated DT40 cells, BLNK is phosphorylated by Syk and not by Btk. PMID: 11434777
    2. Microarray analysis of SCA-2 induced bursal cells showed BLNK to be among the under-expressed genes and this was validated with qRT-PCR. PMID: 19945479
    3. short SLP-65 isoform promotes BCR-induced B-cell apoptosis PMID: 16912232
    4. BLNK recruits active H-Ras to the BCR complex, which is essential for sustained surface expression of BCR in the form of the cap and for the signal leading to functional ERK activation PMID: 19218240
  • 亞細(xì)胞定位：
    Cytoplasm. Cell membrane. Note=BCR activation results in the translocation to membrane fraction.
  • 組織特異性：
    Highly expressed in the bursa, very low expression in ovary and spleen. Expression was variable among B-cell lines. Highly expressed in immature B-cell lines such as DT40 and CL18, low expression was seen in relatively mature B-cell lines, such as 293B9 a
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 亚洲人成77777在线播放网站不卡| 蕾丝av无码专区在线观看| 秋霞无码久久久精品交换| 亚洲日韩欧美在线成人| 国产男女猛烈无遮挡a片漫画| 亚洲性无码av中文字幕| 午夜男女爽爽影院免费视频| 波多野av一区二区无码| 亚洲精品天堂成人片av在线播放| 69精品国产久热在线观看| 2020精品国产午夜福利在线观看| 激情国产一区二区三区四区| 中文字幕人妻熟女在线| 99久久久无码国产精品试看| 97精品国产久热在线观看| 国产精品久久久久久不卡盗摄| 成人影片一区免费观看| 四虎一区二区成人免费影院网址| 国产美熟女乱又伦av果冻传媒| 天天狠天天透天天伊人| 中文在线√天堂| 欧美一道本一区二区三区| 亚洲欧美成人中文日韩电影网站| 国产涩涩视频在线观看| 国产精品久久久久久久久岛| 无码少妇高潮浪潮av久久| 精品一二三区久久aaa片| 亚洲国产无线乱码在线观看| 国产美女嘘嘘嘘嘘嘘| 色哟哟最新在线观看入口| 中国极品少妇xxxxx| 777米奇影视第四色| 亚洲日本乱码在线观看| 色悠久久久久综合网国产| 天堂中文8资源在线8| 国产99青草视频在线播放视| 在线精品自偷自拍无码中文| 扒开双腿吃奶呻吟做受视频| 久久老子午夜精品无码怎么打| 欧美人与动性xxxxx交性| 色偷偷888欧美精品久久久|