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  4. Recombinant Cerastes cerastes Phospholipase A2 1

Recombinant Cerastes cerastes Phospholipase A2 1

  • 中文名稱：
    Recombinant Cerastes cerastes Phospholipase A2 1
  • 貨號：
    CSB-YP315506CGI
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Cerastes cerastes Phospholipase A2 1
  • 貨號：
    CSB-EP315506CGI
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Cerastes cerastes Phospholipase A2 1
  • 貨號：
    CSB-EP315506CGI-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Cerastes cerastes Phospholipase A2 1
  • 貨號：
    CSB-BP315506CGI
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Cerastes cerastes Phospholipase A2 1
  • 貨號：
    CSB-MP315506CGI
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    N/A
  • Uniprot No.：
  • 別名：
    Acidic phospholipase A2 CC-PLA2-1; svPLA2; EC 3.1.1.4; Phosphatidylcholine 2-acylhydrolase
  • 種屬：
    Cerastes cerastes (Horned desert viper)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    17-137
  • 氨基酸序列
    NLYQ FGKMIKHKTG KSALLSYSAY GCYCGWGGQG KPQDATDHCC FVHDCCYGEV SGCYPKTAFT LKFENQDIIC GDEDPCNRAV CECDRVAAIC FGENVNTSDK KYLFYSSSYC EEESEQC
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Snake venom phospholipase A2 (PLA2) that inhibits blood coagulation and platelet aggregation induced by ADP and arachidonic acid. Inhibits tumor cell adhesion and migration in a dose-dependent manner. Abolishes the attachment of human brain microvascular endothelial cells (HBMEC) to fibrinogen (IC(50)=0.12 uM) and dramatically reduces it adhesion to fibronectin (IC(50)=0.12 uM), whereas no effect is observed on type I collagen, vitronectin or laminin 1. Also blocks the cell migration toward fibronectin and fibrinogen. These effects are not dependent of the catalytic activity, but are mediated by alpha-5/beta-1 (ITGA5/ITGB1) and alpha-v-containing (ITGAV) integrins. Also shows anti-angiogenic activity in chicken chorioallantoix membrane assay. Has a relatively high enzymatic activity. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Phospholipase A2 family, Group II subfamily, D49 sub-subfamily
  • 組織特異性：
    Expressed by the venom gland.


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