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  4. Recombinant Candida albicans Histone acetyltransferase type B catalytic subunit (HAT1)

Recombinant Candida albicans Histone acetyltransferase type B catalytic subunit (HAT1)

  • 中文名稱：
    白念珠菌HAT1重組蛋白
  • 貨號：
    CSB-YP691391CZD
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    白念珠菌HAT1重組蛋白
  • 貨號：
    CSB-EP691391CZD
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    白念珠菌HAT1重組蛋白
  • 貨號：
    CSB-EP691391CZD-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    白念珠菌HAT1重組蛋白
  • 貨號：
    CSB-BP691391CZD
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    白念珠菌HAT1重組蛋白
  • 貨號：
    CSB-MP691391CZD
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    HAT1; CAALFM_C104670WA; CaO19.779; CaO19.8401; Histone acetyltransferase type B catalytic subunit; EC 2.3.1.48
  • 種屬：
    Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-413
  • 氨基酸序列
    MSSAKEQSSV TAALQPEQWT TSSNEALKLF VTNPEAALNF QPTFTYPIFG DAETIYGYKD LDIFLCFDHY TFKPFLNIKY SAKLTDDPEI IDIKKTIDEF LPKSTIFKDE VKWVDSIKEE KDNGYKIPGK LIDSFSENDK EYDIYKIDLK SDNGYELHQR LQILVLLFIE AGSFIDAKDE LWNLYVLYEK DNKSTSNNEP SIVGFTTAYN YWKYPGAKKF DSTEQESRIK ISQFIILPIY QGQGLGQLFY SHLFDKWLAQ DDIIEVVVED PNESFDDLRD RADLKRLNTS EQFDFKAVTP KVDKEWVEKT RRALKLEKRQ FARLLEIILL YKLKHGYPGI TKRDVRLFIK KRLYDKNKEG LATLDDNTKK DKLQTAYQAL EDDYYRILGD LKLNIKREND EEETDTVSKK QKV
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Catalytic component of the histone acetylase B (HAT-B) complex. Acetylates 'Lys-14' of histone H4 which is required for telomeric silencing. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.
  • 基因功能參考文獻：
    1. we discover a novel function for the chromatin assembly-associated histone acetyltransferase complex NuB4 catalytic subunit HAT1 in oxidative stress response, antifungal drug tolerance as well as in fungal virulence PMID: 26473952
    2. findings show that C. albicans requires a fully functional HAT1 complex for efficient repair of DNA damages, normal cell proliferation and maintenance of the yeast morphology. PMID: 23075292
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    HAT1 family
  • 數據庫鏈接：


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