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  4. Recombinant Cadherin-related hmr-1 (hmr-1), partial

Recombinant Cadherin-related hmr-1 (hmr-1), partial

  • 中文名稱：
    秀麗隱桿線蟲hmr-1重組蛋白
  • 貨號：
    CSB-YP839271CXY
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲hmr-1重組蛋白
  • 貨號：
    CSB-EP839271CXY
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲hmr-1重組蛋白
  • 貨號：
    CSB-EP839271CXY-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲hmr-1重組蛋白
  • 貨號：
    CSB-BP839271CXY
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲hmr-1重組蛋白
  • 貨號：
    CSB-MP839271CXY
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    hmr-1
  • Uniprot No.：
  • 別名：
    hmr-1; W02B9.1; Cadherin-related hmr-1; Protein Hammerhead
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 675
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Required for adherens junction assembly and connecting adherens junctions to the cytoskeleton.; Isoform a is required for cell migration during body enclosure and cell shape changes during body elongation. Required for proper localization of other junctional components, such as hmp-1, hmp-2, jac-1 and pac-1. Recruitment of pac-1 is required to establish cell polarity, independent of its role in cell adhesion. Required for primodial germ cell ingression and adherence to endodermal cells during gastrulation.; Isoform b is involved in axonal guidance in a subset of motor neurons.
  • 基因功能參考文獻：
    1. HMP-1 bound filamentous actin with an affinity in the single micromolar range, even when complexed with the beta-catenin homolog HMP-2 or when present in a complex of HMP-2 and the cadherin homolog HMR-1, indicating that HMP-1 binding to F-actin is not allosterically regulated by the HMP-2.HMR-1 complex. PMID: 28298447
    2. sax-7 and hmr-1 function redundantly in blastomere compaction and non-muscle myosin accumulation during C. elegans gastrulation. PMID: 20515680
  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein. Cell junction, adherens junction. Cell junction.; [Isoform a]: Cell junction, adherens junction.
  • 組織特異性：
    Isoform b is neuron-specific. Isoform a is located in epidermal cells (at protein level).
  • 數據庫鏈接：

    KEGG: cel:CELE_W02B9.1

    STRING: 6239.W02B9.1b

    UniGene: Cel.17110



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