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  4. Recombinant Bungarus candidus Alpha-delta-bungarotoxin-1 (alpha-delta-Bgt-1)

Recombinant Bungarus candidus Alpha-delta-bungarotoxin-1 (alpha-delta-Bgt-1)

  • 中文名稱：
    Recombinant Bungarus candidus Alpha-delta-bungarotoxin-1(alpha-delta-Bgt-1)
  • 貨號：
    CSB-YP375069BPN
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Bungarus candidus Alpha-delta-bungarotoxin-1(alpha-delta-Bgt-1)
  • 貨號：
    CSB-EP375069BPN
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Bungarus candidus Alpha-delta-bungarotoxin-1(alpha-delta-Bgt-1)
  • 貨號：
    CSB-EP375069BPN-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Bungarus candidus Alpha-delta-bungarotoxin-1(alpha-delta-Bgt-1)
  • 貨號：
    CSB-BP375069BPN
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Bungarus candidus Alpha-delta-bungarotoxin-1(alpha-delta-Bgt-1)
  • 貨號：
    CSB-MP375069BPN
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    N/A
  • Uniprot No.：
  • 別名：
    Alpha-elapitoxin-Bc2a; Alpha-EPTX-Bc2a; Alpha-delta-bungarotoxin-1; Alpha-delta-Bgt-1; Fragment
  • 種屬：
    Bungarus candidus (Malayan krait)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    3-75
  • 氨基酸序列
    LLCYKTPS PINAETCPPG ENLCYTKMWC DAWCSSRGKV IELGCAATCP SKKPYEEVTC CSTDKCNPHP KQRPG
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Binds to muscular and neuronal nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission (Ref.2, PubMed:30944155). Reversibly blocks chick and mouse muscle nicotinic acetylcholine receptors (Ref.2, PubMed:30944155). Blocks muscle type nAChR with an IC(50)=30 nM, when heterologously expressed in oocytes. Also binds with high affinity to alpha-7/CHRNA7 nAChRs. In addition, shows a weak inhibition of neuronal alpha-3-beta-2/CHRNA3-CHRNB2 nAChR (IC(50)=2.9 uM). Selectively binds to alpha-1-delta subunit interface of the mouse muscle nicotinic acetylcholine receptor, with a 10-fold higher affinity for the adult than for the fetal receptors (Ref.2, PubMed:30944155). In vivo, when intraperitoneally injected into mice, causes flaccid paralysis and respiratory distress, followed by death within 2-4 hours.
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Snake three-finger toxin family, Long-chain subfamily, Type II alpha-neurotoxin sub-subfamily
  • 組織特異性：
    Expressed by the venom gland.


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