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  4. Recombinant Brucella abortus biovar 1 6,7-dimethyl-8-ribityllumazine synthase 2 (ribH2)

Recombinant Brucella abortus biovar 1 6,7-dimethyl-8-ribityllumazine synthase 2 (ribH2)

  • 中文名稱：
    流產(chǎn)布魯氏菌1ribH2重組蛋白
  • 貨號：
    CSB-YP352829BWS
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    流產(chǎn)布魯氏菌1ribH2重組蛋白
  • 貨號：
    CSB-EP352829BWS
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    流產(chǎn)布魯氏菌1ribH2重組蛋白
  • 貨號：
    CSB-EP352829BWS-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    流產(chǎn)布魯氏菌1ribH2重組蛋白
  • 貨號：
    CSB-BP352829BWS
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    流產(chǎn)布魯氏菌1ribH2重組蛋白
  • 貨號：
    CSB-MP352829BWS
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ribH2
  • Uniprot No.：
  • 別名：
    ribH2; ribH; ribH-2; BruAb2_0535; 6,7-dimethyl-8-ribityllumazine synthase 2; DMRL synthase 2; LS 2; Lumazine synthase 2; EC 2.5.1.78; BLS; Type II lumazine synthase
  • 種屬：
    Brucella abortus biovar 1 (strain 9-941)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-158
  • 氨基酸序列
    MNQSCPNKTS FKIAFIQARW HADIVDEARK SFVAELAAKT GGSVEVEIFD VPGAYEIPLH AKTLARTGRY AAIVGAAFVI DGGIYRHDFV ATAVINGMMQ VQLETEVPVL SVVLTPHHFH ESKEHHDFFH AHFKVKGVEA AHAALQIVSE RSRIAALV
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. Displays low catalytic activity in comparison with the isozyme RibH1. Is a highly immunogenic protein. Activates dendritic cells (DCs) in vitro, increasing the levels of costimulatory molecules and the secretion of proinflammatory cytokines, and recruits DCs, B cells and CD8+ T cells in vivo, both effects in a TLR4-dependent manner. Induces the cross presentation of covalently attached peptides and generates a strong and long-lasting humoral immune response without adjuvants; TLR4 signaling is necessary for the induction of the cytotoxic response but not for antigen cross presentation. Elicits a TLR4-mediated protective response against B16 melanoma in mice, slowing tumor growth and prolonging mice survival.
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    DMRL synthase family
  • 數(shù)據(jù)庫鏈接：


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