在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Bovine Tyrosyl-DNA phosphodiesterase 2 (TDP2)

Recombinant Bovine Tyrosyl-DNA phosphodiesterase 2 (TDP2)

  • 中文名稱：
    牛TDP2重組蛋白
  • 貨號：
    CSB-YP420812BO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛TDP2重組蛋白
  • 貨號：
    CSB-EP420812BO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    牛TDP2重組蛋白
  • 貨號：
    CSB-EP420812BO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛TDP2重組蛋白
  • 貨號：
    CSB-BP420812BO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛TDP2重組蛋白
  • 貨號：
    CSB-MP420812BO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    TDP2
  • Uniprot No.：
  • 別名：
    TDP2; TTRAP; Tyrosyl-DNA phosphodiesterase 2; Tyr-DNA phosphodiesterase 2; EC 3.1.4.-; 5'-tyrosyl-DNA phosphodiesterase; 5'-Tyr-DNA phosphodiesterase; TRAF and TNF receptor-associated protein
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-364
  • 氨基酸序列
    MERNSGPEAG PEAELEEGEP EVKKRKLMCV EFASVASCDA AVAQCYLAEN DWEMERALNS YFEPAVEESA SESRPESLSE PGSCVDLTKE ETNDSISSKT STSEDKSVQQ EDGSVFSFIT WNIDGLDMNN LLERARGVCS YLTLYSPDVI FLQEVIPPYY AYLKKKASSY KIITGREEGY FTAIMLKKSR VKFKSQEIIP FPNTQMMRNL LCVHVSVSGN ELCLMTSHLE STRGHAKERM NQFKMVLEKM QEAPGSATVI FAGDTNLRDQ EVTKCGGLPN NILDVWEFLG KPKHCQYTWD TQMNSNLGIA ANCKLRFDRI FFRAAAEGGH IIPQSLDLLG LEKLDCGRFP SDHWGLLCTL DVIL
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DNA double-strand breaks/DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Thereby, protects the transcription of many genes involved in neurological development and maintenance from the abortive activity of TOP2. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DSBs due to DNA damage by radiation and free radicals. Has preference for single-stranded DNA or duplex DNA with a 4 base pair overhang as substrate. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. Constitutes the major if not only 5'-tyrosyl-DNA phosphodiesterase in cells. Also acts as an adapter by participating in the specific activation of MAP3K7/TAK1 in response to TGF-beta: associates with components of the TGF-beta receptor-TRAF6-TAK1 signaling module and promotes their ubiquitination dependent complex formation. Involved in non-canonical TGF-beta induced signaling routes. May also act as a negative regulator of ETS1 and may inhibit NF-kappa-B activation. Acts as a regulator of ribosome biogenesis following stress.
  • 亞細胞定位：
    Nucleus. Nucleus, PML body. Nucleus, nucleolus. Cytoplasm.
  • 蛋白家族：
    CCR4/nocturin family
  • 數據庫鏈接：


主站蜘蛛池模板： 国产精品调教视频一区| 加勒比无码一区二区三区| 国产专区国产av| 欧美一区内射最近更新| 免费无码一区二区三区蜜桃大| 在阳台上玩弄人妻的乳球| 国产欧美另类久久久精品丝瓜| 顶级欧美做受xxx000| 50岁熟妇大白屁股真爽| 老熟妇仑乱一区二区视頻| 国产成a人亚洲精v品无码| 亚洲综合日韩久久成人av| 56pao国产成视频永久| 国产又黄又大又粗视频| 婷婷丁香社区| 国产av无码专区亚洲精品| 久久无码无码久久综合综合| 天堂在线www资源| 欧美人与性动交α欧美精品| 国产999精品久久久久久| 人与禽性视频77777| 国产成人最新三级在线视频| 午夜爽爽爽男女免费观看影院| 熟女少妇丰满一区二区| 国产9 9在线 | 中文| 欧美日韩无套内射另类| 日本熟妇色一本在线视频| 99精品国产福久久久久久| 无码粉嫩虎白一线天在线观看| 人妻系列无码专区久久五月天| 国产一区二区三区四区精华| 2019国产品在线视频| 亚洲另类无码一区二区三区| 亚洲这里只有久热精品伊人| 日本少妇无码精品12p| 欧美野性肉体狂欢大派对| 久久综合亚洲色一区二区三区| 狂野欧美性猛xxxx乱大交| 亚洲精品色播一区二区| 欧美成人午夜免费影院手机在线看 | 精品国产一区二区av麻豆 |