在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Bovine Sterol regulatory element-binding protein cleavage-activating protein (SCAP), partial

Recombinant Bovine Sterol regulatory element-binding protein cleavage-activating protein (SCAP), partial

  • 中文名稱：
    牛SCAP重組蛋白
  • 貨號：
    CSB-YP020758BO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛SCAP重組蛋白
  • 貨號：
    CSB-EP020758BO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    牛SCAP重組蛋白
  • 貨號：
    CSB-EP020758BO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛SCAP重組蛋白
  • 貨號：
    CSB-BP020758BO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛SCAP重組蛋白
  • 貨號：
    CSB-MP020758BO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    SCAP; Sterol regulatory element-binding protein cleavage-activating protein; SCAP; SREBP cleavage-activating protein
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Escort protein required for cholesterol as well as lipid homeostasis. Regulates export of the SCAP-SREBP complex from the endoplasmic reticulum to the Golgi upon low cholesterol, thereby regulating the processing of sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2. At high sterol concentrations, formation of a ternary complex with INSIG (INSIG1 or INSIG2) leads to mask the ER export signal in SCAP, promoting retention of the complex in the endoplasmic reticulum. Low sterol concentrations trigger release of INSIG, a conformational change in the SSD domain of SCAP, unmasking of the ER export signal, promoting recruitment into COPII-coated vesicles and transport of the SCAP-SREBP to the Golgi: in the Golgi, SREBPs are then processed, releasing the transcription factor fragment of SREBPs from the membrane, its import into the nucleus and up-regulation of LDLR, INSIG1 and the mevalonate pathway. Binds cholesterol via its SSD domain.
  • 基因功能參考文獻(xiàn)：
    1. Although the knockdown of PKM2 had no effect on MAC-T cell growth, the reduced expression of PKM2 attenuated the mRNA and protein expression of key enzymes involved in sterol synthesis through the SREBP pathway. PMID: 29383471
  • 亞細(xì)胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.
  • 蛋白家族：
    WD repeat SCAP family
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 国产av精品一区二区三区小说| 国产精品久久久久久妇女| 无码高潮又爽又黄a片软件| 好紧好爽免费午夜视频| 亚欧成人无码av在线播放| 日日摸天天爽天天爽视频| 午夜福利国产成人无码gif动图 | 日日碰狠狠躁久久躁蜜桃| 亚洲黑人巨大videos| 六月丁香亚洲综合在线视频| 欧美老肥熟妇多毛xxxxx| 国产农村妇女高潮大叫| 精品国产制服丝袜高跟| 欧洲美熟女乱又伦av影片| 人妻三级日本香港三级极| 先锋影音av最新资源| 中文字字幕人妻中文| 日本理伦片午夜理伦片| 日日婷婷夜日日天干| 国产精品免费无码二区| 业余 自由 性别 成熟偷窥| 夜夜爽狠狠天天婷婷五月| 麻豆国产成人av在线播放欲色 | 中文字幕无码毛片免费看| 国产成人啪精品视频免费视频| 亚洲最大av网站在线观看| 欧美老熟妇欲乱高清视频| 国产内射999视频一区| av无码中文字幕不卡一区二区三区| 亚洲国产欧美在线人成app | 精品国产一区二区三区无码 | 久久久久影院美女国产主播| 亚洲中文字幕久久精品无码喷水| 熟妇人妻久久中文字幕| 精品国产av最大网站| 午夜福利av无码一区二区| 236宅宅理论片免费| 四虎永久在线精品视频免费观看| 亚洲色无码专区在线观看| 国产av无码国产av毛片| 久久久欧美国产精品人妻噜噜|