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  4. Recombinant Bovine Serpin A3-3 (SERPINA3-3)

Recombinant Bovine Serpin A3-3 (SERPINA3-3)

  • 中文名稱：
    牛SERPINA3-3重組蛋白
  • 貨號：
    CSB-YP670270BO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛SERPINA3-3重組蛋白
  • 貨號：
    CSB-EP670270BO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    牛SERPINA3-3重組蛋白
  • 貨號：
    CSB-EP670270BO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛SERPINA3-3重組蛋白
  • 貨號：
    CSB-BP670270BO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛SERPINA3-3重組蛋白
  • 貨號：
    CSB-MP670270BO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SERPINA3-3
  • Uniprot No.：
  • 別名：
    SERPINA3-3; Serpin A3-3; Endopin-1B; Muscle endopin-1B; mEndopin-1B
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    25-411
  • 氨基酸序列
    LPENVV VKDRHRRVDG HTLASSNTDF AFSLYKQLAL KNPNKNVMFS PLSVSMALAF LSLGARGPTL TEILEGLKFN LTEIQETQIH QGFQHLLQAL NRPRNQLQLS VGNAMFVQEE LKLLDKFIED ARVLYSSEAF PTNFRDPEAA KSLINDYVKN KTQGKIEELF KDLSPRTELV LVNYVYFKAQ WKTRFDPKHT EQAEFHVSDN KTVEVPMMTL DLETPYFRDE ELGCTLVELT YTSNDSALFI LPDKGKMQDL EAKLTPEMLT RWRNSLQPRR IHELYLPKFS IKSNYELNDT LSQMGIKKIF TDADLSGITG TADLVVSQVV HGAALDVDEE GTEGAAATGI GIERTFLRII VRVNRPFLIA VVLKDTQSII FLGKVTNPSE A
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Serine protease inhibitor. Strongly inhibits elastase and trypsin stoichiometrically at the molar ratio of 1:1. Acts as a moderate inhibitor of plasmin and chymotrypsin. Does not inhibit thrombin, urokinase, kallikrein, tissue plasminogen activator, cathepsin G or the cysteine proteases papain, cathepsin B or cathepsin L.
  • 基因功能參考文獻：
    1. In this report, by site-directed mutagenesis of recombinant SERPINA3-3, with substitution D371A, the study demonstrates the importance of D371 for the intermolecular linkage observed in denaturing and reducing conditions. PMID: 22505318
    2. Data demonstrate the strong inhibition of human initiator and effector caspases 3 and 8 by bovine SERPINA3-1 and A3-3. PMID: 19665028
  • 亞細胞定位：
    Cytoplasmic vesicle, secretory vesicle, chromaffin granule. Secreted.
  • 蛋白家族：
    Serpin family
  • 數據庫鏈接：


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