在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Bovine Serine/threonine-protein kinase NLK (NLK), partial

Recombinant Bovine Serine/threonine-protein kinase NLK (NLK), partial

  • 中文名稱：
    牛NLK重組蛋白
  • 貨號：
    CSB-YP015859BO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛NLK重組蛋白
  • 貨號：
    CSB-EP015859BO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    牛NLK重組蛋白
  • 貨號：
    CSB-EP015859BO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛NLK重組蛋白
  • 貨號：
    CSB-BP015859BO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛NLK重組蛋白
  • 貨號：
    CSB-MP015859BO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    NLKSerine/threonine-protein kinase NLK; EC 2.7.11.24; Nemo-like kinase
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Serine/threonine-protein kinase that regulates a number of transcription factors with key roles in cell fate determination. Positive effector of the non-canonical Wnt signaling pathway, acting downstream of WNT5A, MAP3K7/TAK1 and HIPK2. Activation of this pathway causes binding to and phosphorylation of the histone methyltransferase SETDB1. The NLK-SETDB1 complex subsequently interacts with PPARG, leading to methylation of PPARG target promoters at histone H3K9 and transcriptional silencing. The resulting loss of PPARG target gene transcription inhibits adipogenesis and promotes osteoblastogenesis in mesenchymal stem cells (MSCs). Negative regulator of the canonical Wnt/beta-catenin signaling pathway. Binds to and phosphorylates TCF7L2/TCF4 and LEF1, promoting the dissociation of the TCF7L2/LEF1/beta-catenin complex from DNA, as well as the ubiquitination and subsequent proteolysis of LEF1. Together these effects inhibit the transcriptional activation of canonical Wnt/beta-catenin target genes. Negative regulator of the Notch signaling pathway. Binds to and phosphorylates NOTCH1, thereby preventing the formation of a transcriptionally active ternary complex of NOTCH1, RBPJ/RBPSUH and MAML1. Negative regulator of the MYB family of transcription factors. Phosphorylation of MYB leads to its subsequent proteolysis while phosphorylation of MYBL1 and MYBL2 inhibits their interaction with the coactivator CREBBP. Other transcription factors may also be inhibited by direct phosphorylation of CREBBP itself. Acts downstream of IL6 and MAP3K7/TAK1 to phosphorylate STAT3, which is in turn required for activation of NLK by MAP3K7/TAK1. Upon IL1B stimulus, cooperates with ATF5 to activate the transactivation activity of C/EBP subfamily members. Phosphorylates ATF5 but also stabilizes ATF5 protein levels in a kinase-independent manner.
  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily
  • 數據庫鏈接：


主站蜘蛛池模板： 玩弄人妻少妇500系列| 新国产精品视频福利免费| 日韩一区二区三区北条麻妃| 人妻出轨av中文字幕| 又黄又湿啪啪响18禁| 亚洲精品国产高清一线久久| 亚洲丰满熟女一区二区v| 日本丰满白嫩大屁股ass| 亚洲一卡2卡三卡四卡精品| 精品国产你懂的在线观看| 亚洲精品久久久久中文字幕m男| 又嫩又硬又黄又爽的视频| 久久精品蜜芽亚洲国产av| 国产男女免费完整视频| 日产精品高潮呻吟av久久| 日韩精品一区二区大桥未久| 国产午夜福利伦理300| 色婷婷香蕉在线一区二区| 精品国产乱码久久久久久郑州公司 | 国产精品久久久av久久久| 国产麻豆 9l 精品三级站| 亚洲国产精品无码专区成人| 免费人成视频19674不收费 | 97色偷偷色噜噜狠狠爱网站| 久久综合久久美利坚合众国| 国产美女a做受大片观看| 国产制服丝袜欧美在线观看| 国产亚洲产品影市在线产品 | 久久久欧美国产精品人妻噜噜| 色噜噜狠狠色综合网| 亚洲性无码av在线dvd| 97精品人妻系列无码人妻| 国产精品久久久久av| 亚洲另类欧美小说图片区| 无码三级中文字幕在线观看| 夜夜高潮夜夜爽夜夜爱爱一区 | 欧美亚洲日本国产黑白配| 久久99热只有频精品8| 国产欧美日韩一区二区三区| 国产免费毛卡片| 亚洲狠狠色成人综合网|