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  4. Recombinant Bovine Recombining binding protein suppressor of hairless (RBPJ)

Recombinant Bovine Recombining binding protein suppressor of hairless (RBPJ)

  • 中文名稱：
    牛RBPJ重組蛋白
  • 貨號：
    CSB-YP664862BO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛RBPJ重組蛋白
  • 貨號：
    CSB-EP664862BO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    牛RBPJ重組蛋白
  • 貨號：
    CSB-EP664862BO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛RBPJ重組蛋白
  • 貨號：
    CSB-BP664862BO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛RBPJ重組蛋白
  • 貨號：
    CSB-MP664862BO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    RBPJ; RBPSUH; Recombining binding protein suppressor of hairless; J kappa-recombination signal-binding protein; RBP-J kappa
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-487
  • 氨基酸序列
    MAPVVTGKFG ERPPPKRLTR EAMRNYLKER GDQTVLILHA KVAQKSYGNE KRFFCPPPCV YLMGSGWKKK KEQMERDGCS EQESQPCAFI GIGNSDQEMQ QLNLEGKNYC TAKTLYISDS DKRKHFMLSV KMFYGNSDDI GVFLSKRIKV ISKPSKKKQS LKNADLCIAS GTKVALFNRL RSQTVSTRYL HVEGGNFHAS SQQWGAFYIH LLDDDESEGE EFTVRDGYIH YGQTVKLVCS VTGMALPRLI IRKVDKQTAL LDADDPVSQL HKCAFYLKDT ERMYLCLSQE RIIQFQATPC PKEPNKEMIN DGASWTIIST DKAEYTFYEG MGPVLAPVTP VPVVESLQLN GGGDVAMLEL TGQNFTPNLR VWFGDVEAET MYRCGESMLC VVPDISAFRE GWRWVRQPVQ VPVTLVRNDG IIYSTSLTFT YTPEPGPRPH CSAAGAILRA NSSQVPPNES NTNSEGSYTN VSTNSTSVTS STATVVS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA. Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen). Negatively regulates the phagocyte oxidative burst in response to bacterial infection by repressing transcription of NADPH oxidase subunits.
  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    Su(H) family
  • 數據庫鏈接：


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