在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Bovine Receptor-type tyrosine-protein phosphatase-like N (PTPRN), partial

Recombinant Bovine Receptor-type tyrosine-protein phosphatase-like N (PTPRN), partial

  • 中文名稱：
    牛PTPRN重組蛋白
  • 貨號：
    CSB-YP019059BO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛PTPRN重組蛋白
  • 貨號：
    CSB-EP019059BO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    牛PTPRN重組蛋白
  • 貨號：
    CSB-EP019059BO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛PTPRN重組蛋白
  • 貨號：
    CSB-BP019059BO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛PTPRN重組蛋白
  • 貨號：
    CSB-MP019059BO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    PTPRN; Receptor-type tyrosine-protein phosphatase-like N; R-PTP-N; Islet cell autoantigen 512; ICA512) [Cleaved into: ICA512-N-terminal fragment; ICA512-NTF); ICA512-transmembrane fragment; ICA512-TMF); ICA512-cleaved cytosolic fragment; ICA512-CCF)]
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a role in vesicle-mediated secretory processes. Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancreatic islets. Required for the accumulation of normal levels of insulin-containing vesicles and preventing their degradation. Plays a role in insulin secretion in response to glucose stimuli. Required for normal accumulation of the neurotransmitters norepinephrine, dopamine and serotonin in the brain. In females, but not in males, required for normal accumulation and secretion of pituitary hormones, such as luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Required to maintain normal levels of renin expression and renin release. Seems to lack intrinsic enzyme activity. May regulate catalytic active protein-tyrosine phosphatases such as PTPRA through dimerization.; ICA512-TMF regulates dynamics and exocytosis of insulin secretory granules (SGs); binding of ICA512-TMF to SNTB2/beta-2-syntrophin is proposed to restrain SGs mobility and exocytosis by tethering them to the actin cytoskeleton depending on UTRN; the function is inhibited by cytoplasmic ICA512-CFF dimerizing with ICA512-TMF and displacing SNTB2.; ICA512-CCF translocated to the nucleus promotes expression of insulin and other granule-related genes; the function implicates binding to and regulating activity of STAT5B probably by preventing its dephosphorylation and potentially by inducing its sumoylation by recruiting PIAS4. Enhances pancreatic beta-cell proliferation by converging with signaling by STAT5B and STAT3. ICA512-CCF located in the cytoplasm regulates dynamics and exocytosis of insulin secretory granules (SGs) by dimerizing with ICA512-TMF and displacing SNTB2 thus enhancing SGs mobility and exocytosis.
  • 亞細胞定位：
    Membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type I membrane protein. Perikaryon. Cell projection, axon. Cell junction, synapse. Cell membrane; Single-pass type I membrane protein. Endosome.; [ICA512-transmembrane fragment]: Cytoplasmic vesicle, secretory vesicle membrane.; [ICA512-cleaved cytosolic fragment]: Nucleus.
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Receptor class 8 subfamily
  • 組織特異性：
    Detected in pituitary (at protein level).
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲国产精品成人久久| 日韩欧美激情兽交| 亚洲欧美成人一区二区在线电影 | 两个黑人大战嫩白金发美女| 国产亚洲精品久久777777| 2021国产精品视频网站| 日韩人妻不卡一区二区三区| 国产一区二区三区精品视频| 国偷自产av一区二区三区 | a在线亚洲男人的天堂| 久天啪天天久久99久孕妇| 特级毛片在线大全免费播放| 内射中出日韩无国产剧情| 欧洲亚洲1卡二卡三卡2021| 国产做a爰片久久毛片a片美国| 四川丰满少妇被弄到高潮| 国产日产欧洲无码视频| 极品少妇扒开粉嫩小泬视频| 成 人影片 aⅴ毛片免费观看| 久久精品国产av一区二区三区| 99精品国产一区二区| a v 在线视频 亚洲免费| 精品久久久久香蕉网| 亚洲国产无线乱码在线观看| 午夜dj高清免费观看视频| 在线永久无码不卡av| 同性男男黄g片免费网站| 亚洲精品字幕| 中文有码人妻字幕在线| 欧美搡bbbbb搡bbbbb| 精品人妻大屁股白浆无码| 久久青青草原国产最新片完整| 久久国产亚洲精品无码| 免费的黄网站在线观看| 久久视频这里有精品33| 99国产揄拍国产精品人妻| 亚洲最大的成人网| 日韩 欧美 国产 一区三| 尤物蜜芽国产成人精品区| 插我一区二区在线观看| 樱花草在线社区www韩国|