在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Bovine Receptor-type tyrosine-protein phosphatase-like N (PTPRN), partial

  • 中文名稱:
    牛PTPRN重組蛋白
  • 貨號:
    CSB-YP019059BO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    牛PTPRN重組蛋白
  • 貨號:
    CSB-EP019059BO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    牛PTPRN重組蛋白
  • 貨號:
    CSB-EP019059BO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    牛PTPRN重組蛋白
  • 貨號:
    CSB-BP019059BO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    牛PTPRN重組蛋白
  • 貨號:
    CSB-MP019059BO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    PTPRN; Receptor-type tyrosine-protein phosphatase-like N; R-PTP-N; Islet cell autoantigen 512; ICA512) [Cleaved into: ICA512-N-terminal fragment; ICA512-NTF); ICA512-transmembrane fragment; ICA512-TMF); ICA512-cleaved cytosolic fragment; ICA512-CCF)]
  • 種屬:
    Bos taurus (Bovine)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plays a role in vesicle-mediated secretory processes. Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancreatic islets. Required for the accumulation of normal levels of insulin-containing vesicles and preventing their degradation. Plays a role in insulin secretion in response to glucose stimuli. Required for normal accumulation of the neurotransmitters norepinephrine, dopamine and serotonin in the brain. In females, but not in males, required for normal accumulation and secretion of pituitary hormones, such as luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Required to maintain normal levels of renin expression and renin release. Seems to lack intrinsic enzyme activity. May regulate catalytic active protein-tyrosine phosphatases such as PTPRA through dimerization.; ICA512-TMF regulates dynamics and exocytosis of insulin secretory granules (SGs); binding of ICA512-TMF to SNTB2/beta-2-syntrophin is proposed to restrain SGs mobility and exocytosis by tethering them to the actin cytoskeleton depending on UTRN; the function is inhibited by cytoplasmic ICA512-CFF dimerizing with ICA512-TMF and displacing SNTB2.; ICA512-CCF translocated to the nucleus promotes expression of insulin and other granule-related genes; the function implicates binding to and regulating activity of STAT5B probably by preventing its dephosphorylation and potentially by inducing its sumoylation by recruiting PIAS4. Enhances pancreatic beta-cell proliferation by converging with signaling by STAT5B and STAT3. ICA512-CCF located in the cytoplasm regulates dynamics and exocytosis of insulin secretory granules (SGs) by dimerizing with ICA512-TMF and displacing SNTB2 thus enhancing SGs mobility and exocytosis.
  • 亞細胞定位:
    Membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type I membrane protein. Perikaryon. Cell projection, axon. Cell junction, synapse. Cell membrane; Single-pass type I membrane protein. Endosome.; [ICA512-transmembrane fragment]: Cytoplasmic vesicle, secretory vesicle membrane.; [ICA512-cleaved cytosolic fragment]: Nucleus.
  • 蛋白家族:
    Protein-tyrosine phosphatase family, Receptor class 8 subfamily
  • 組織特異性:
    Detected in pituitary (at protein level).
  • 數據庫鏈接:


主站蜘蛛池模板: 精品三级久久久久电影网| 国产精品久久久久久人妻精品| 亚洲裸男自慰gv网站| 日韩精品人成在线播放| 天堂中文最新版在线官网在线| 国产精品美女www爽爽爽视频| 亚洲欧美日韩综合在线一| 亚洲中文字幕无码永久| 337p粉嫩日本欧洲亚福利 | 久热国产vs视频在线观看| 国产精品久久国产精品99盘| 国产成 人 综合 亚洲| 亚洲跨种族黑人xxxxx| 亚洲熟妇中文字幕五十中出| 日日噜噜噜夜夜爽爽狠狠| 国产免费一区二区三区免费视频 | 无码午夜福利片| 性色做爰片在线观看ww| 国产精品自在在线午夜出白浆| 曰本无码不卡高清av一二| 国产精品一区二区av片| 国产av一区二区精品久久凹凸| 日本亚洲色大成网站www久久| 国产精品久久久久久无码| 国产毛片精品av一区二区| 国产l精品国产亚洲区| 亚洲美女被黑人巨大在线播放 | 无码少妇一区二区浪潮免费| 国产超碰人人做人人爱一二区视品| 好吊妞人成视频在线观看27du| 久久99国产乱子伦精品免费| av无码小缝喷白浆在线观看| 久久不见久久见免费视频6无删减 丰满日韩放荡少妇无码视频 | 717影院理论午夜伦八戒| 一区二区在线 | 欧洲| 无码人妻精品一区二区三| 久久99亚洲含羞草影院| 香蕉在线依人视频| 人妻一本久道久久综合久久鬼色| 99久久综合狠狠综合久久止| 三级做a全过程在线观看|