在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Bovine Protein arginine N-methyltransferase 5 (PRMT5), partial

  • 中文名稱:
    牛PRMT5重組蛋白
  • 貨號:
    CSB-YP018734BO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    牛PRMT5重組蛋白
  • 貨號:
    CSB-EP018734BO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    牛PRMT5重組蛋白
  • 貨號:
    CSB-EP018734BO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    牛PRMT5重組蛋白
  • 貨號:
    CSB-BP018734BO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    牛PRMT5重組蛋白
  • 貨號:
    CSB-MP018734BO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    PRMT5; SKB1Protein arginine N-methyltransferase 5; PRMT5; EC 2.1.1.320; Histone-arginine N-methyltransferase PRMT5; Shk1 kinase-binding protein 1 homolog; SKB1 homolog
  • 種屬:
    Bos taurus (Bovine)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H and may regulate its transcriptional elongation properties. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. Methylates RPS10. Attenuates EGF signaling through the MAPK1/MAPK3 pathway acting at 2 levels. First, monomethylates EGFR; this enhances EGFR 'Tyr-1197' phosphorylation and PTPN6 recruitment, eventually leading to reduced SOS1 phosphorylation. Second, methylates RAF1 and probably BRAF, hence destabilizing these 2 signaling proteins and reducing their catalytic activity. Required for induction of E-selectin and VCAM-1, on the endothelial cells surface at sites of inflammation. Methylates HOXA9. Methylates and regulates SRGAP2 which is involved in cell migration and differentiation. Acts as a transcriptional corepressor in CRY1-mediated repression of the core circadian component PER1 by regulating the H4R3 dimethylation at the PER1 promoter. Methylates GM130/GOLGA2, regulating Golgi ribbon formation. Methylates H4R3 in genes involved in glioblastomagenesis in a CHTOP- and/or TET1-dependent manner. Symmetrically methylates POLR2A, a modification that allows the recruitment to POLR2A of proteins including SMN1/SMN2 and SETX. This is required for resolving RNA-DNA hybrids created by RNA polymerase II, that form R-loop in transcription terminal regions, an important step in proper transcription termination. Along with LYAR, binds the promoter of gamma-globin HBG1/HBG2 and represses its expression. Symmetrically methylates NCL. Methylates TP53; methylation might possibly affect TP53 target gene specificity. Involved in spliceosome maturation and mRNA splicing in prophase I spermatocytes through the catalysis of the symmetrical arginine dimethylation of SNRPB (small nuclear ribonucleoprotein-associated protein B) and the interaction with tudor domain-containing protein TDRD6.
  • 亞細胞定位:
    Cytoplasm. Nucleus. Golgi apparatus.
  • 蛋白家族:
    Class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase family
  • 數據庫鏈接:


主站蜘蛛池模板: 国产一区二区三区在线视頻| 中文字幕亚洲乱码熟女在线| 亚洲另类无码专区国内精品 | 美国一区二区三区无码视频| 三上悠亚ssⅰn939无码播放| 狠狠狠狼鲁亚洲综合网| 亚洲国产成人精品无码区在线秒播| 免费人成黄页在线观看国产| 精品国模一区二区三区| 日本乱人伦在线观看| 开心五月综合亚洲| 开心色婷婷色五月激情| 一本一本久久a久久精品综合麻豆| 日韩网红少妇无码视频香港 | 女被男啪到哭的视频网站| 精品噜噜噜噜久久久久久久久| 日本久久久久久久久久加勒比| 欧洲精品成人免费视频在线观看| 国产麻豆成人传媒免费观看 | 野外做受又硬又粗又大视幕| 狠狠躁夜夜躁人人爽天天天天| 国产成人综合欧美精品久久| 免费的av网站在线观看国产精品| 国产播放隔着超薄丝袜进入| 中国内地毛片免费高清| 四虎永久在线精品免费网址| 免费啪视频在线观看视频日本 | 成人区人妻精品一区二区不卡视频| 特黄做受又粗又长又大又硬| 人人莫人人擦人人看| 最新av偷拍av偷窥av网站| 日日摸日日添日日碰9学生露脸| 国内精品乱码卡一卡2卡麻豆| 日韩人妻无码免费视频一区二区| 超碰97人人射妻| 人妻少妇乱子伦无码专区| 国产午夜高清高清在线观看| 青青青国产精品一区二区| 激情毛片无码专区| 伊人久久大香线蕉综合bd高清 | 精品国产一区二区三区av性色 |