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  2. 蛋白
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  4. Recombinant Bovine Pleckstrin homology-like domain family A member 2 (PHLDA2)

Recombinant Bovine Pleckstrin homology-like domain family A member 2 (PHLDA2)

  • 中文名稱：
    牛PHLDA2重組蛋白
  • 貨號：
    CSB-YP611737BO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛PHLDA2重組蛋白
  • 貨號：
    CSB-EP611737BO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    牛PHLDA2重組蛋白
  • 貨號：
    CSB-EP611737BO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛PHLDA2重組蛋白
  • 貨號：
    CSB-BP611737BO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛PHLDA2重組蛋白
  • 貨號：
    CSB-MP611737BO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    PHLDA2
  • Uniprot No.：
  • 別名：
    PHLDA2; IPLPleckstrin homology-like domain family A member 2; Imprinted in placenta and liver protein
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-142
  • 氨基酸序列
    MRSPGEVLRE GELEKRSDSL LQVWKKKRGV LTTDRLRLFP TGPGARPKEL RFHSILKVDC VERTGKYVYF TIVTTDRKEI DFRCAGESYW NASITLALID FQNRRAMQDF RSRRERAAAA AAAAAAAAAA EQEPEAGPGG QP
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids.
  • 基因功能參考文獻：
    1. genes critical for placental development were altered in nuclear transfer placentas, including an imprinted gene. Allele-specific changes in the permissive histone mark in the PHLDA2 promoter indicate misregulation of imprinting in clones. PMID: 28442058
    2. imprinting status of four cattle genes (Tssc4,Nap1l4, Phlda2 and Osbpl5) in seven types of tissues, were assessed in cattle. PMID: 26440077
    3. proper expression levels of the imprinted genes CDKN1C and PHLDA2 are critical for embryo development PMID: 23894493
    4. Pleckstrin homology-like domain family A member 2 (PHLDA2) gene is expressed across a range of cattle fetal tissues and stages. It provides the first evidence that PHLDA2 is a monoallelically expressed imprinted gene in cattle fetal tissues and placenta. PMID: 22497461
  • 亞細胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein.
  • 蛋白家族：
    PHLDA2 family
  • 數據庫鏈接：

    KEGG: bta:618810

    STRING: 9913.ENSBTAP00000041685

    UniGene: Bt.1702



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