在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Bovine Nucleotide-binding oligomerization domain-containing protein 2 (NOD2), partial

In Stock
  • 貨號:
    CSB-EP732277BO
  • 規格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Caspase recruitment domain-containing protein 15
  • 種屬:
    BO-Bos taurus (Bovine)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    36.8 kDa
  • 表達區域:
    1-191aa
  • 氨基酸序列
    MCAQDAFQTQRSQLVELLVSGSLEGFESILDRLLSREVLSWEDYEGLSLVGQPISHLARRLLDTIWNKGTWGCEQLTAAVREAQADSQPPELPSSWDPHSPHPARDLQSHRPAIVRRLYGHVEGVLDLTQQRGFISQYETDEIRRPIFTSSQRARRLLDLATVKANGLAAFLLQCIQELPVPLALPFEDAA
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-KSI-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3, INAVA and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response. Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages. Component of an autophagy-mediated antibacterial pathway together with ATG16L1. Plays also a role in sensing single-stranded RNA (ssRNA) from viruses. Interacts with mitochondrial antiviral signaling/MAVS, leading to activation of interferon regulatory factor-3/IRF3 and expression of type I interferon.
  • 基因功能參考文獻:
    1. These results revealed that thermal stress increased the expression levels of NOD1/2 genes and acute inflammatory cytokines which sheds some light on their role on immune response of the host cells during thermal stress.These preliminary studies indicated that the immune-related genes differentially expressed during thermal stress among native and crossbred cattle. PMID: 27853874
    2. Data indicate six single-nucleotide polymorphisms (SNPs) in the caspase recruitment domain 15 protein (CARD15) gene associated with susceptibility to bovine tuberculosis (BTB) in Chinese Holstein cows. PMID: 26244859
    3. Data indicate that the Nod2 signaling adaptor protein (NOD2) G-->A at position 1594 bp plays a critical role in increasing 305-day milk yields. PMID: 25966125
    4. Genetic variation and putative regulatory regions in bovine CARD15. PMID: 16897345
    5. This study indicates that SNP c.3020A>T might play a role in the host response against mastitis and further detailed studies are needed to understand its functional mechanisms PMID: 18005441
    6. A significant association was found between two polymorphisms of CARD15 and paratuberculosis status; cows with the heterozygous genotype were 3.35 times more likely to be infected than cows with the reference genotype. PMID: 18926647

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Membrane. Basolateral cell membrane.
  • 數據庫鏈接:


主站蜘蛛池模板: 黑人玩弄出轨人妻松雪| 伊人久久综合无码成人网| 亚洲 日本 欧美 中文幕| 99久久久国产精品免费蜜臀| 亚洲熟女精品中文字幕| 少妇人妻中文字幕hd| 亚洲第一福利网站在线观看 | 成人免费国产精品视频| 久久人妻无码中文字幕| 久久亚洲国产最新网站之一| 日韩人妻ol丝袜av一二区| 久9视频这里只有精品| 高清无码一区二区在线观看吞精| 极品少妇扒开粉嫩小泬视频 | 天天爱天天做久久狠狠做| 成人奭片免费观看| 亚洲日韩中文字幕无码一区| 久久久中文字幕日本无吗| av片日韩一区二区三区在线观看| 亚洲午夜久久久精品影院| 鲁丝一区二区三区免费| 亚洲精品无码久久千人斩| 人妻无码手机在线中文| 欧美人禽杂交狂配| 人妻av中文字幕无码专区| 人人妻人人爽人人做夜欢视频| 欧美 日韩 亚洲 在线| 玩弄丰满奶水的女邻居| 久久国产加勒比精品无码 | 精品一区二区三区自拍图片区| 国产精品ⅴ无码大片在线看| 亚洲色成人网站www永久蜜芽| 日本乱码一区二区三区不卡| 黄a大片av永久免费| 男人添女人下部高潮视频| 伊人久久大香线蕉aⅴ色| 奶头又大又白喷奶水av| 国产sm主人调教女m视频| 国产亚洲日韩在线aaaa| 一本加勒比hezyo无码人妻| 曰韩无码av片免费播放不卡|