在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Bovine MAP kinase-activated protein kinase 3 (MAPKAPK3)

Recombinant Bovine MAP kinase-activated protein kinase 3 (MAPKAPK3)

  • 中文名稱：
    牛MAPKAPK3重組蛋白
  • 貨號：
    CSB-YP663576BO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛MAPKAPK3重組蛋白
  • 貨號：
    CSB-EP663576BO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    牛MAPKAPK3重組蛋白
  • 貨號：
    CSB-EP663576BO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛MAPKAPK3重組蛋白
  • 貨號：
    CSB-BP663576BO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛MAPKAPK3重組蛋白
  • 貨號：
    CSB-MP663576BO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    MAPKAPK3MAP kinase-activated protein kinase 3; MAPK-activated protein kinase 3; MAPKAP kinase 3; MAPKAP-K3; MAPKAPK-3; MK-3; EC 2.7.11.1
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-384
  • 氨基酸序列
    MDVETAEEQG GPAPPSGVPC GPCSAGAPAL GGRREPKKYA VTDDYQLSKQ VLGLGVNGKV LECFHRRTGQ KCALKLLYDS PKARQEVDHH WQASGGPHIV RILDVYENMH HSKRCLLIIM ECMEGGELFS RIQERGDQAF TEREAAEIMR DIGTAIQFLH SRNIAHRDVK PENLLYTSKD KDAVLKLTDF GFAKETTQNA LQTPCYTPYY VAPEVLGPEK YDKSCDMWSL GVIMYILLCG FPPFYSNTGQ AISPGMKRRI RLGQYGFPSP EWSEVSEDAK QLIRLLLKTD PTERLTITQF MNHPWINQSM VVPQTPLHTA RVLQEDRDHW DEVKEEMTSA LATMRVDYDQ VKIKDLKTSN NRLLNKRRKK QAGSSSGSQG CNNQ
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Stress-activated serine/threonine-protein kinase involved in cytokines production, endocytosis, cell migration, chromatin remodeling and transcriptional regulation. Following stress, it is phosphorylated and activated by MAP kinase p38-alpha/MAPK14, leading to phosphorylation of substrates. Phosphorylates serine in the peptide sequence, Hyd-X-R-X(2)-S, where Hyd is a large hydrophobic residue. MAPKAPK2 and MAPKAPK3, share the same function and substrate specificity, but MAPKAPK3 kinase activity and level in protein expression are lower compared to MAPKAPK2. Phosphorylates HSP27/HSPB1, KRT18, KRT20, RCSD1, RPS6KA3, TAB3 and TTP/ZFP36. Mediates phosphorylation of HSP27/HSPB1 in response to stress, leading to dissociate HSP27/HSPB1 from large small heat-shock protein (sHsps) oligomers and impair their chaperone activities and ability to protect against oxidative stress effectively. Involved in inflammatory response by regulating tumor necrosis factor (TNF) and IL6 production post-transcriptionally: acts by phosphorylating AU-rich elements (AREs)-binding proteins, such as TTP/ZFP36, leading to regulate the stability and translation of TNF and IL6 mRNAs. Phosphorylation of TTP/ZFP36, a major post-transcriptional regulator of TNF, promotes its binding to 14-3-3 proteins and reduces its ARE mRNA affinity leading to inhibition of dependent degradation of ARE-containing transcript. Involved in toll-like receptor signaling pathway (TLR) in dendritic cells: required for acute TLR-induced macropinocytosis by phosphorylating and activating RPS6KA3. Also acts as a modulator of Polycomb-mediated repression.
  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family
  • 數據庫鏈接：


主站蜘蛛池模板： 国产熟女内射oooo| 国产人妻xxxx精品hd| 亚洲另类欧美综合久久图片区| 中文字幕 人妻熟女| 中文字幕乱码亚洲精品一区| 人妻三级日本香港三级极| 亚洲一线二线三线品牌精华液久久久| 国产精品人人做人人爽人人添| 国产精品久久久久久无码 | 久久婷婷五月综合色奶水99啪| 日韩国产人妻一区二区三区| 久久久无码精品亚洲日韩蜜桃 | 成人午夜福利院在线观看| 中文无码日韩欧免费视频| 成人欧美一区二区三区的电影| 国产亚洲精品aaaaaaa片| 亚洲欧美日韩综合一区在线| 少妇私密推油呻吟在线播放| 伊人情人综合网| 国产一卡三卡四卡无卡精品| 日本乱人伦aⅴ精品| 99国产精品久久久久久久成人热| 国产成人人人97超碰超爽8| 国产成人mv视频在线观看| 吃奶呻吟打开双腿做受视频| 久久中文字幕人妻熟av女蜜柚m| 99re6热视频这里只精品首页 | 亚洲中文字幕无码永久在线| 欧美老熟妇喷水| 久久成人国产精品无码| 中文字幕精品一二三四五六七八| 午夜成人理论福利片| 亚洲 丝袜 制服 欧美 另类| 欧美丰满熟妇xxxx性ppx人| 亚洲日韩国产av无码无码精品| 18禁止进入1000部高潮网站| 欧美性生交xxxxx无码久久久| 欧美无遮挡很黄裸交视频| 无码专区aaaaaa免费视频| 麻豆丰满少妇chinese| 麻花传媒mv国产免费观看视频|