在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Bovine Insulin-like growth factor II (IGF2), partial

Recombinant Bovine Insulin-like growth factor II (IGF2), partial

  • 中文名稱：
    牛IGF2重組蛋白
  • 貨號：
    CSB-YP011088BO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛IGF2重組蛋白
  • 貨號：
    CSB-EP011088BO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛IGF2重組蛋白
  • 貨號：
    CSB-BP011088BO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    IGF2Insulin-like growth factor II; IGF-II; Erythrotropin) [Cleaved into: Insulin-like growth factor II; Preptin]
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    Partial
  • 表達區域：
    25-91
  • 氨基酸序列
    AYRPSE TLCGGELVDT LQFVCGDRGF YFSRPSSRIN RRSRGIVEEC CFRSCDLALL ETYCATPAKS E
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF2 is influenced by placental lactogen. Also involved in tissue differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver. Acts as a ligand for integrin which is required for IGF2 signaling. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation. Inhibits myoblast differentiation and modulates metabolism via increasing the mitochondrial respiration rate.; Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
  • 基因功能參考文獻：
    1. Methylation pattern in a CpG island of the IGF2 gene in cumulus cells from 1-3 mm and >/= 8.0 mm follicles and the effects of in vitro maturation on this pattern. PMID: 24174298
    2. Our results provide evidence that polymorphisms in the IGF2 gene are associated with growth traits, and may be used for marker-assisted selection in beef cattle breeding program PMID: 24374893
    3. The identification of the polymorphisms in the IGF2 gene that were significantly associated with growth traits in cattle. PMID: 23957672
    4. Polymorphisms in the IGF2 gene are associated with cattle growth traits. PMID: 23900197
    5. The LEP, IGF2 and CCL2 genes showed allelic expression imbalance in liver, kidney and pituitary glands of Polish Holstein-Friesian bulls. PMID: 23184004
    6. Sex-sorting procedure by flow cytometry did not affect the overall DNA methylation patterns of the IGF2 and IGF2R genes, although individual variation in their methylation patterns among bulls was observed. PMID: 22128039
    7. The reduction in IGFs mRNA level after 5 days of life in the duodenum (IGF-1 and IGF-2) and in the jejunum (IGF-1) was associated with reduction in villi length (duodenum and jejunum) and the increase of crypt depth (duodenum). PMID: 22439332
    8. Changes in the methylation pattern of IGF2 during in vitro maturation were different between incompetent and competent oocytes, and this characteristic may be useful as a molecular marker in studies of oocyte competence in cattle. PMID: 20833870
    9. Data describes the long-term changes to skeletal muscle growth and IGF1, 2, 1R, and 2R mRNA expression in progeny after exposure to high and low levels of maternal nutrient intake during the first two trimesters of gestation in the bovine. PMID: 21056085
    10. findings support work which suggests that the insulin-like growth factor 2 locus is an important biological regulator of milk production in dairy cattle PMID: 20822563
    11. effects of insulin, IGF-I and IGF-II on apoptosis and cell proliferation in bovine blastocysts in vitro PMID: 12112582
    12. IGF2 is subjected to extensive transcriptional regulation through multiple promoters, alternative splicing and polyadenylation, as well as genetic imprinting.IGF2 regulation is age-, tissue-, promoter-, and allele-specific PMID: 16120826
    13. Identification of a previously unknown differentially methylated region in exon 10 of the bovine IGF2 gene. PMID: 16644179
    14. Indel polymorphism associated with breeding value in bulls. PMID: 17242995
    15. The role of insulin-like growth factor 2 (IGF2) and the regulation of the IGF2 receptor (IGF2R) during follicular development were studied. PMID: 17360960
    16. Embryonic tissues from NT-derived embryos had higher expression of IGF-II mRNA than in vitro production embryonic tissues. PMID: 17628655
    17. The effect of single nucleotide polymorphisms in 6 genes and their associations with production factors in beef cattle are reported. PMID: 17785604
    18. study to assess the mRNA expression of IGF-I, IGF-II, IGF-IR and IGF-IIR in bovine oocytes and different stages of preimplantation embryos PMID: 19013732
    19. Dats detected that SNPs of IGF2 gene has close relationship with carcass and meat quality traits in Qinchuan cattle PMID: 19073573
    20. Hypomethylation trends in the intergenic region of the imprinted IGF2 and H19 genes in cloned cattle. PMID: 19282114
    21. Among embryos developing in vivo, the level of DNA methylation in the IGF2 intragenic DMR was significantly lower in female than in male blastocysts PMID: 19341790

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Insulin family
  • 數據庫鏈接：


主站蜘蛛池模板： 久久99国产亚洲高清观看首页| 丰满岳乱妇在线观看中字无码 | 无码少妇一区二区三区芒果| 日本爽爽爽爽爽爽在线观看免 | 久久青青草原国产最新片完整| 一卡二卡三卡视频| 日本丶国产丶欧美色综合| 日韩高清成片免费视频| 97se亚洲国产综合自在线观看| 999久久久免费精品国产| 国产精品99久久免费观看| 少妇被躁爽到高潮| 香港三日本三级少妇三级66| 国产男女免费完整视频网页| 日本特黄aaaaaa片在线观看| 99久久精品美女高潮喷水| 亚洲中文无码av在线| 亚欧av无码乱码在线观看性色| 少妇扒开双腿让我看个够| 国产精品福利视频萌白酱| 国内露脸中年夫妇交换| 国产色综合天天综合网| 国产成人麻豆亚洲综合精品| 国产成人最新三级在线视频| 偷看农村女人做爰毛片色| 2019nv天堂香蕉在线观看| 欧美噜噜久久久xxx| 亚洲伦无码中文字幕另类| 欧美香蕉爽爽人人爽| 精品久久久久久无码人妻蜜桃| 亚洲视频在线观看| 无码国内精品久久人妻| 色天使久久综合给合久久97色| 一本色道久久综合亚州精品蜜桃| 亚洲一区二区三区在线播放无码| 亚洲综合无码精品一区二区三区| 屁屁影院ccyy备用地址| 丰满人妻熟妇乱又仑精品| 国产超碰人人做人人爱| 欧美日韓性视頻在線| 欧洲免费无线码在线一区|