在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Bovine Insulin-induced gene 1 protein (INSIG1), partial

Recombinant Bovine Insulin-induced gene 1 protein (INSIG1), partial

  • 中文名稱：
    牛INSIG1重組蛋白
  • 貨號：
    CSB-YP011745BO1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛INSIG1重組蛋白
  • 貨號：
    CSB-EP011745BO1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    牛INSIG1重組蛋白
  • 貨號：
    CSB-EP011745BO1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛INSIG1重組蛋白
  • 貨號：
    CSB-BP011745BO1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛INSIG1重組蛋白
  • 貨號：
    CSB-MP011745BO1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    INSIG1
  • Uniprot No.：
  • 別名：
    INSIG1; Insulin-induced gene 1 protein; INSIG-1
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of SCAP and degradation of HMGCR. Acts as a negative regulator of cholesterol biosynthesis by mediating the retention of the SCAP-SREBP complex in the endoplasmic reticulum, thereby blocking the processing of sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2. Binds oxysterol, including 25-hydroxycholesterol, regulating interaction with SCAP and retention of the SCAP-SREBP complex in the endoplasmic reticulum. In presence of oxysterol, interacts with SCAP, retaining the SCAP-SREBP complex in the endoplasmic reticulum, thereby preventing SCAP from escorting SREBF1/SREBP1 and SREBF2/SREBP2 to the Golgi. Sterol deprivation or phosphorylation by PCK1 reduce oxysterol-binding, disrupting the interaction between INSIG1 and SCAP, thereby promoting Golgi transport of the SCAP-SREBP complex, followed by processing and nuclear translocation of SREBF1/SREBP1 and SREBF2/SREBP2. Also regulates cholesterol synthesis by regulating degradation of HMGCR: initiates the sterol-mediated ubiquitin-mediated endoplasmic reticulum-associated degradation (ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligases AMFR/gp78 and/or RNF139. Also regulates degradation of SOAT2/ACAT2 when the lipid levels are low: initiates the ubiquitin-mediated degradation of SOAT2/ACAT2 via recruitment of the ubiquitin ligases AMFR/gp78.
  • 基因功能參考文獻：
    1. In Nanyang Chinese cattle, seven common haplotypes were identified in the INSIG1 gene based on four coding region SNPs. PMID: 22642648
  • 亞細胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    INSIG family
  • 數據庫鏈接：


主站蜘蛛池模板： 99噜噜噜在线播放| 亚洲高潮喷水无码av电影| av无码人妻中文字幕| 午夜三级a三级三点在线观看| 图片区 小说区 区 亚洲五月| 中出人妻中文字幕无码| 亚洲不乱码卡一卡二卡4卡5卡| 天干天干夜啦天干天干国产| 2021国产精品成人免费视频| 欧美黑人大战白嫩在线| 成熟老妇女视频| 成年无码动漫av片在线观看羞羞| 玩弄丰满奶水的女邻居| 亚洲成年轻人电影网站www| 国产一在线精品一区在线观看| 中文字幕无线码一区2020青青| 日韩在线永久免费播放| 少妇爱做高清免费视频| 国产乱沈阳女人高潮乱叫老| 狠狠色噜噜狠狠狠狠777米奇| 国内高清久久久久久| 暖暖视频 免费 日本社区| 国内精品久久人妻互换| 唐人社导航福利精品| 超碰色偷偷男人的天堂| 水蜜桃精品一二三| 免费天堂无码人妻成人av电影| 激情偷乱人伦小说视频在线| 免费无码av片在线观看| 亚洲精品久久yy5099| 国产乱辈通伦影片在线播放亚洲| 国产成人精品一区二区在线小狼| 少妇被黑人到高潮喷出白浆| 特级欧美插插插插插bbbbb| 天堂www中文资源| 亚洲中文字幕无码不卡电影| 亚洲va欧美va天堂v国产综合| 国产精品一区二区香蕉| 噜噜色综合天天综合网mp3| 中字乱码视频| 国产韩国精品一区二区三区久久|