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  4. Recombinant Bovine Estrogen receptor beta (ESR2), partial

Recombinant Bovine Estrogen receptor beta (ESR2), partial

  • 中文名稱：
    牛ESR2重組蛋白
  • 貨號：
    CSB-YP896422BO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛ESR2重組蛋白
  • 貨號：
    CSB-EP896422BO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    牛ESR2重組蛋白
  • 貨號：
    CSB-EP896422BO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛ESR2重組蛋白
  • 貨號：
    CSB-BP896422BO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛ESR2重組蛋白
  • 貨號：
    CSB-MP896422BO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    ESR2; NR3A2Estrogen receptor beta; ER-beta; Nuclear receptor subfamily 3 group A member 2
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
  • 基因功能參考文獻：
    1. The mRNA expression of ER-alpha and ER-beta in the hypothalamus of developing male and female bovines, is reported. PMID: 25363750
    2. ER-alpha is detected predominantly in the soma whereas ER-beta is only present in the nucleus of a few cells in the frontal cortex. PMID: 21397601
    3. fetal ovary of cattle has the steroidogenic enzyme aromatase to convert androgens to estradiol-17beta, and estrogen receptors alpha and beta to facilitate an estrogen response within the fetal ovary PMID: 19299095
    4. there are different levels of ERalpha, ERbeta and PR in bovine oviducts at different cycle stages in vivo PMID: 12711014
    5. ER may play a role in the rapid effects of resveratrol in EC and some of the atheroprotective effects of resveratrol may be mediated through rapid activation of ER signaling in EC PMID: 15615701
    6. The expression of estrogen and progesterone receptors in ovarian follicular structures from cows with cystic ovarian disease (COD) and a comparison of these with normal ovarian structures are reported. PMID: 17491080
    7. These data indicate that PGF2alpha, TNFalpha and IFNgamma regulate ERalpha and ERbeta mRNA expressions in bovine luteal cells. PMID: 17598955
    8. Roles of IGF-I and the estrogen, androgen and IGF-I receptors in estradiol-17beta- and trenbolone acetate-stimulated proliferation of cultured bovine satellite cells. PMID: 18403176

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  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Nuclear hormone receptor family, NR3 subfamily
  • 組織特異性：
    Present in granulosa cells of antral follicles in various stages of follicular growth.
  • 數據庫鏈接：

    KEGG: bta:281146

    STRING: 9913.ENSBTAP00000005899

    UniGene: Bt.541



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