在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Bovine Breast cancer type 1 susceptibility protein homolog (BRCA1), partial

  • 中文名稱:
    Recombinant Bovine Breast cancer type 1 susceptibility protein homolog(BRCA1) ,partial
  • 貨號:
    CSB-YP769686BO
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Bovine Breast cancer type 1 susceptibility protein homolog(BRCA1) ,partial
  • 貨號:
    CSB-EP769686BO
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Bovine Breast cancer type 1 susceptibility protein homolog(BRCA1) ,partial
  • 貨號:
    CSB-EP769686BO-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Bovine Breast cancer type 1 susceptibility protein homolog(BRCA1) ,partial
  • 貨號:
    CSB-BP769686BO
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Bovine Breast cancer type 1 susceptibility protein homolog(BRCA1) ,partial
  • 貨號:
    CSB-MP769686BO
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    BRCA1; Breast cancer type 1 susceptibility protein homolog; EC 2.3.2.27; RING-type E3 ubiquitin transferase BRCA1
  • 種屬:
    Bos taurus (Bovine)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Regulates centrosomal microtubule nucleation. Required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. Required for FANCD2 targeting to sites of DNA damage. Inhibits lipid synthesis by binding to inactive phosphorylated ACACA and preventing its dephosphorylation. Contributes to homologous recombination repair (HRR) via its direct interaction with PALB2, fine-tunes recombinational repair partly through its modulatory role in the PALB2-dependent loading of BRCA2-RAD51 repair machinery at DNA breaks. Component of the BRCA1-RBBP8 complex which regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage via BRCA1-mediated ubiquitination of RBBP8. Acts as a transcriptional activator.
  • 基因功能參考文獻:
    1. Investigation on BRCA1 SNPs and its effects on mastitis in Chinese commercial cattle. PMID: 22583824
    2. The gene-specific SNP marker analysis showed a significant association of BRCA1 C28300A with milk somatic cell scores. PMID: 22327776
    3. In general, OC use, childbearing and breastfeeding do not differ between BRCA1/2 carriers and non-carriers with ovarian cancer. However, the effects of tubal ligation may differ between BRCA1 carriers and non-carriers. PMID: 12946038
    4. Bovine BRCA1 was phosphorylated and nuclear speckling was enhanced in response to DNA-damaging agents.These results provide evidence that phosphorylation and nuclear relocalization are highly conserved features of the BRCA1 response to genotoxic stress. PMID: 12955082
  • 亞細胞定位:
    Nucleus. Chromosome. Cytoplasm.
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 久久久国产精品麻豆a片| 日韩va中文字幕无码电影| 肥老熟妇伦子伦456视频| 亚洲国产aⅴ成人精品无吗 | 强伦人妻一区二区三区视频18| 亚洲一二三四2021不卡| 亚洲αⅴ无码乱码在线观看性色| 亚洲一二三四2021不卡| 天堂亚洲2017在线观看| 国产人在线成免费视频| 少妇富婆高级按摩出水高潮 | 色狠狠色噜噜av天堂一区| 久久精品第一国产久精国产宅男66| 中文字幕无码日韩欧免费软件 | 欧美成人aa大片| 中国熟妇人妻xxxxx| 成年男女免费视频网站| 国产男女性潮高清免费网站| 另类 专区 欧美 制服| 色www永久免费视频首页| 无码三级av电影在线观看| 中文无码天天av天天爽| 日韩av无码中文无码不卡电影| 麻豆国产人妻欲求不满谁演的| 后入内射欧美99二区视频| 久久亚洲道色综合久久| 激烈的性高湖波多野结衣| 最新国产麻豆aⅴ精品无码| 无码播放一区二区三区| 国产免费无遮挡吸乳视频| 色偷拍 自怕 亚洲 10p| 色综合天天天天综合狠狠爱| 国色天香社区视频| 成熟人妻av无码专区| 日本午夜免费啪视频在线| 潮喷大喷水系列无码久久精品| a在线观看免费网站大全| 亚洲а∨天堂久久精品2021| 国产精品无码素人福利| 日韩av第一页在线播放| 亚洲欧美另类精品二区|