在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Bovine Actin-related protein 2 (ACTR2)

  • 中文名稱:
    Recombinant Bovine Actin-related protein 2(ACTR2)
  • 貨號:
    CSB-YP001248BO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Bovine Actin-related protein 2(ACTR2)
  • 貨號:
    CSB-EP001248BO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Bovine Actin-related protein 2(ACTR2)
  • 貨號:
    CSB-EP001248BO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Bovine Actin-related protein 2(ACTR2)
  • 貨號:
    CSB-BP001248BO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Bovine Actin-related protein 2(ACTR2)
  • 貨號:
    CSB-MP001248BO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    ACTR2
  • Uniprot No.:
  • 別名:
    ACTR2; ARP2Actin-related protein 2; Actin-like protein 2
  • 種屬:
    Bos taurus (Bovine)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-394
  • 氨基酸序列
    MDSQGRKVVV CDNGTGFVKC GYAGSNFPEH IFPALVGRPI IRSTTKVGNI EIKDLMVGDE ASELRSMLEV NYPMENGIVR NWDDMKHLWD YTFGPEKLNI DTRNCKILLT EPPMNPTKNR EKIVEVMFET YQFSGVYVAI QAVLTLYAQG LLTGVVVDSG DGVTHICPVY EGFSLPHLTR RLDIAGRDIT RYLIKLLLLR GYAFNHSADF ETVRMIKEKL CYVGYNIEQE QKLALETTVL VESYTLPDGR IIKVGGERFE APEALFQPHL INVEGVGVAE LLFNTIQAAD IDTRSEFYKH IVLSGGSTMY PGLPSRLERE LKQLYLERVL KGDVEKLSKF KIRIEDPPRR KHMVFLGGAV LADIMKDKDN FWMTRQEYQE KGVRVLEKLG VTVR
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. In podocytes, required for the formation of lamellipodia downstream of AVIL and PLCE1 regulation. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
  • 基因功能參考文獻:
    1. crystal structure of Arp2/3 complex PMID: 26323303
    2. These results demonstrate an important role for CRMP-1 in Listeria actin comet tail formation and open the possibility that CRMP-1 controls cell motility by modulating Arp2/3 activation. PMID: 26598519
    3. The GMF-Arp2 interface reveals how the ADF-H actin-binding domain in GMF is exploited to specifically recognize Arp2/3 complex and not actin. PMID: 23893131
    4. interacts with contactin and N-WASp PMID: 12176354
    5. conserved surface residues to search for functionally important structural elements PMID: 14757065
    6. Data show that L. monocytogenes motility can be separated into an Arp2/3-dependent nucleation phase, and an Arp2/3-independent elongation phase which is dependent upon fascin. PMID: 15117967
    7. crystal structures of Arp2/3 complex with bound ATP or ADP PMID: 15505213
    8. WASp stabilizes p35-dependent closure of the complex, holding Arp2 and Arp3 closer together to nucleate an actin filament. PMID: 15592479
    9. domain rearrangements of Arp2 and Arp3 result in a closed conformational state consistent with an "actin-dimer" model for the active state PMID: 17251352

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Cell projection. Nucleus.
  • 蛋白家族:
    Actin family, ARP2 subfamily
  • 數據庫鏈接:


主站蜘蛛池模板: 久久狼人大香伊蕉国产| 免费国产va在线观看| 无码国模产在线观看免费| 国产强伦姧在线观看无码| 国产精品久久久久一区二区三区| 无码 制服 丝袜 国产 另类| 成人网站免费大全日韩国产| 国产亚洲精品久久久久久入口| 欧美xxxx做受欧美人妖| 色妺妺在线视频| 欧美牲交a欧美牲交aⅴ图片 | 国产亚洲精品第一综合麻豆| 强行糟蹋人妻hd中文字幕 | 人妻激情另类乱人伦人妻| 狠狠爱亚洲五月婷婷av| 国产清纯美女遭强到高潮| 伊人久久大香线蕉无码| 九一九色国产| 少妇激情av一区二区三区| 无人去码一码二码三码区| 在线成人一区二区| 老子午夜精品无码| 伊在人天堂亚洲香蕉精品区 | 无码中文字幕av免费放dvd| 国产老熟女伦老熟妇露脸| 亚洲精品乱码久久久久久| 超清制服丝袜无码av福利网| 国产顶级熟妇高潮xxxxx| 99国产精品自在自在久久| 无码av中文字幕免费放| 久久无码喷吹高潮播放不卡| 蜜桃视频无码区在线观看| 成人网站免费观看| 国内精品久久久久影院网站| 亚洲欧美日韩在线一区| 国产日韩欧美亚欧在线| 久久综合九色综合欧美婷婷| 少妇精品视频无码专区| 人妻中文字幕无码专区| 精品国产美女av久久久久| 色欲香天天综合网站|