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  4. Recombinant Bothrops jararaca Platelet-aggregating proteinase PA-BJ

Recombinant Bothrops jararaca Platelet-aggregating proteinase PA-BJ

  • 中文名稱：
    Recombinant Bothrops jararaca Platelet-aggregating proteinase PA-BJ
  • 貨號：
    CSB-YP305691BUW
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Bothrops jararaca Platelet-aggregating proteinase PA-BJ
  • 貨號：
    CSB-EP305691BUW
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Bothrops jararaca Platelet-aggregating proteinase PA-BJ
  • 貨號：
    CSB-EP305691BUW-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Bothrops jararaca Platelet-aggregating proteinase PA-BJ
  • 貨號：
    CSB-BP305691BUW
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Bothrops jararaca Platelet-aggregating proteinase PA-BJ
  • 貨號：
    CSB-MP305691BUW
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    N/A
  • Uniprot No.：
  • 別名：
    ; Platelet-aggregating proteinase PA-BJ; EC 3.4.21.-; Snake venom serine protease; SVSP; Fragment
  • 種屬：
    Bothrops jararaca (Jararaca)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    6-237
  • 氨基酸序列
    VVGGR PCKINVHRSL VLLYNSSSLL CSGTLINQEW VLTAAHCDSK NFKMKLGVHS IKIRNKNERT RHPKEKFICP NRKKDDVLDK DIMLIRLNRP VSNSEHIAPL SLPSSPPSVG SVCYVMGWGK ISSTKETYPD VPHCAKINIL DHAVCRAAYT WWPATSTTLC AGILQGGKDT CEGDSGGPLI CNGLQGIVSG GGNPCGQPRK PALYTKVFDY LPWIESIIAG TTTATCP
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Snake venom serine protease that induces platelet aggregation through activation of protease-activated platelet receptors (PAR1/F2R and PAR4/F2RL3). On F2R, the cleavage occurs at Arg41-Ser42 (like thrombin cleavage), and Arg46-Asn47. In normal condition of hemostasis, the cleavage of the Arg41-Ser42 bond liberates a new N-terminus that functions as an agonist. However after envenomation, the cleavage of Arg46-Asn47 bond degrades this potential agonist. This may explain why the snake protease is less potent than thrombin in causing platelet aggregation and release reaction. On F2RL3, a thrombin-like activity has also been proven by calcium release from lung fibroblasts transfected with this receptor. Possesses amidolytic activities.
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Peptidase S1 family, Snake venom subfamily
  • 組織特異性：
    Expressed by the venom gland.


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