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  4. Recombinant Bothrops insularis Zinc metalloproteinase/disintegrin

Recombinant Bothrops insularis Zinc metalloproteinase/disintegrin

  • 中文名稱：
    Recombinant Bothrops insularis Zinc metalloproteinase/disintegrin
  • 貨號(hào)：
    CSB-YP736471BIX
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Bothrops insularis Zinc metalloproteinase/disintegrin
  • 貨號(hào)：
    CSB-EP736471BIX
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Bothrops insularis Zinc metalloproteinase/disintegrin
  • 貨號(hào)：
    CSB-EP736471BIX-B
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Bothrops insularis Zinc metalloproteinase/disintegrin
  • 貨號(hào)：
    CSB-BP736471BIX
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Bothrops insularis Zinc metalloproteinase/disintegrin
  • 貨號(hào)：
    CSB-MP736471BIX
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    N/A
  • Uniprot No.：
  • 別名：
    Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom metalloproteinase insularinase-A; SVMP; EC 3.4.24.-); Disintegrin insularin]
  • 種屬：
    Bothrops insularis (Golden lancehead) (Queimada jararaca)
  • 蛋白長(zhǎng)度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    193-393
  • 氨基酸序列
    QKFSPRYI ELAVVADHGM FTKYNSNLNT IRTRVHEMVN TLNGFFRSVN VDASLANLEV WSKKDLIKVE KDSSKTLTSF GEWRERDLLP RISHDHAQLL TTIVFDQQTI GLAYTAGMCD PRQSVAVVMD HSKKNLRVAV TMAHELGHNL GMDHDDTCTC GAKSCIMAST ISKGLSFEFS KCSQNQYQTY LTDHNPQCIL NKP
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    non-hemorrhagic proteinase that activates prothrombin (F2) calcium-independently. Activates factor X (F10) and hydrolyzes the Aalpha-chain and more slowly the Bbeta-chain of fibrin and fibrinogen without affecting the gamma chain. It induces neither detachment nor apoptosis of human endothelial cells and is also not able to trigger an endothelial proinflammatory cell response. Nitric oxide and prostacyclin levels released by endothelial cells are significantly increased after treatment with insularinase A.; inhibits platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).
  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    Venom metalloproteinase (M12B) family, P-II subfamily, P-IIa sub-subfamily
  • 組織特異性：
    Expressed by the venom gland.


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