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Recombinant Bordetella pertussis Filamentous hemagglutinin (fhaB), partial

In Stock
  • 中文名稱:
    百日咳博德特氏菌fhaB重組蛋白
  • 貨號:
    CSB-EP5214BUA
  • 規格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
    fhaB
  • Uniprot No.:
  • 種屬:
    Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    20.5 kDa
  • 表達區域:
    1752-1879aa
  • 氨基酸序列
    TVKAQNITNKRAALIEAGGNARLTAAVALLNKLGRIRAGEDMHLDAPRIENTAKLSGEVQRKGVQDVGGGEHGRWSGIGYVNYWLRAGNGKKAGTIAAPWYGGDLTAEQSLIEVGKDLYLNAGARKDE
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    C-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Evidence for a role in host-cell binding and infection.
  • 基因功能參考文獻:
    1. review of the literature on FHA with an emphasis on open questions on its structure-function relationships and biological role [review] PMID: 25517899
    2. The TLR2-binding domain of FHA may contribute to immunoprotection against pertussis infection. PMID: 25353353
    3. specific interactions between an N-terminal fragment of filamentous haemagglutinin (FHA) containing the two-partner secretion (TPS) pathway domain and FhaC PMID: 16771844
    4. effect of fhaB on the NFKB pathway in human monocytes, macrophages,epithelial cells; nuclear translocation of RelA, degradation of cytosolic IkappaB alpha, activation of the NF-kappaB pathway. PMID: 19043589
  • 亞細胞定位:
    Cell surface.
  • 數據庫鏈接:

    KEGG: bpe:BP1879

    STRING: 257313.BP1879



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