Recombinant Bacillus subtilis Uncharacterized protein yybT (yybT), partial

中文名稱：

枯草芽孢桿菌gdpP重組蛋白
貨號(hào)：

CSB-YP336300BRJ
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

枯草芽孢桿菌gdpP重組蛋白
貨號(hào)：

CSB-EP336300BRJ
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

枯草芽孢桿菌gdpP重組蛋白
貨號(hào)：

CSB-EP336300BRJ-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

枯草芽孢桿菌gdpP重組蛋白
貨號(hào)：

CSB-BP336300BRJ
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

枯草芽孢桿菌gdpP重組蛋白
貨號(hào)：

CSB-MP336300BRJ
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

gdpP
Uniprot No.：

P37484
別名：

gdpP; yybT; BSU40510; Cyclic-di-AMP phosphodiesterase GdpP; c-di-AMP phosphodiesterase YybT; EC 3.1.4.59; Cyclic-di-AMP hydrolase GdpP; Cyclic-di-AMP phosphodiesterase YybT
種屬：

Bacillus subtilis (strain 168)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP) and to a much lesser extent against cyclic-di-GMP (c-di-GMP) in the DHH/DHHA1 domains. Also has ATPase activity, probably via the GGDEF domain. Overexpression leads to increased sensitivity to methyl methanesulfonate (MMS) and H(2)O(2). Overexpression leads to extreme sensitivity to the beta-lactam antibiotic cefuroxime (CEF), probably dependent on PDE activity. May monitor cellular heme or NO levels. In B.subtilis c-di-AMP is a second messenger that mediates growth, DNA repair and cell wall homeostasis; it is toxic when present in excess.
基因功能參考文獻(xiàn)：
1. sigmaD-dependent antisense transcript modulates expression of the cyclic-di-AMP hydrolase GdpP (YybT). PMID: 22956758
2. The B. subtilis protein YybT, a member of the COG3387 family proteins, exhibits phosphodiesterase activity toward cyclic dinucleotides. PMID: 19901023
亞細(xì)胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

GdpP/PdeA phosphodiesterase family
數(shù)據(jù)庫(kù)鏈接：

KEGG: bsu:BSU40510

STRING: 224308.Bsubs1_010100021861