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  4. Recombinant Bacillus subtilis RsbT co-antagonist protein rsbRA (rsbRA)

Recombinant Bacillus subtilis RsbT co-antagonist protein rsbRA (rsbRA)

  • 中文名稱：
    枯草芽孢桿菌rsbRA重組蛋白
  • 貨號：
    CSB-YP337074BRJ
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    枯草芽孢桿菌rsbRA重組蛋白
  • 貨號：
    CSB-EP337074BRJ
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    枯草芽孢桿菌rsbRA重組蛋白
  • 貨號：
    CSB-EP337074BRJ-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    枯草芽孢桿菌rsbRA重組蛋白
  • 貨號：
    CSB-BP337074BRJ
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    枯草芽孢桿菌rsbRA重組蛋白
  • 貨號：
    CSB-MP337074BRJ
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    rsbRA
  • Uniprot No.：
  • 別名：
    rsbRA; rsbR; ycxR; BSU04670; RsbT co-antagonist protein RsbRA; Stressosome protein RsbRA
  • 種屬：
    Bacillus subtilis (strain 168)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-274
  • 氨基酸序列
    MMSNQTVYQF IAENQNELLQ LWTDTLKELS EQESYQLTDQ VYENISKEYI DILLLSVKDE NAAESQISEL ALRAVQIGLS MKFLATALAE FWKRLYTKMN DKRLPDQEST ELIWQIDRFF SPINTEIFNQ YSISWEKTVS LQKIALQELS APLIPVFENI TVMPLVGTID TERAKRIMEN LLNGVVKHRS QVVLIDITGV PVVDTMVAHH IIQASEAVRL VGAKCLLAGI RPEIAQTIVN LGIDLSQVIT KNTLQKGIQT ALEMTDRKIV SLGE
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Acts as a positive regulator of sigma-B activity in response to salt and heat stress by stimulating the activity of the RsbT kinase toward RsbS in vitro.; One of 4 functionally non-identical RsbR paralogs, it functions in the environmental signaling branch of the general stress response.; Negative regulator of sigma-B activity. Non-phosphorylated RsbS binds to RsbT, preventing its association with RsbU. Requires any one of RsbRA, RsbRB, RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated, they release RsbT, which can then bind and activate RsbU.
  • 基因功能參考文獻：
    1. mutant cells producing only one of the four paralogous RsbR stressosome proteins showed striking and previously unseen differences. Whereas RsbRA-only cells mimicked the wild type, RsbRC-only cells displayed a slower but sustained overall response composed of repeated activation events in single cells. PMID: 28727759
    2. sigma(B) can be activated by red light via the energy branch of its upstream signaling cascade. PMID: 19948797
  • 數據庫鏈接：


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