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  4. Recombinant Bacillus subtilis Formamidopyrimidine-DNA glycosylase (mutM)

Recombinant Bacillus subtilis Formamidopyrimidine-DNA glycosylase (mutM)

  • 中文名稱：
    枯草芽孢桿菌mutM重組蛋白
  • 貨號：
    CSB-YP518472BRJ
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    枯草芽孢桿菌mutM重組蛋白
  • 貨號：
    CSB-EP518472BRJ
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    枯草芽孢桿菌mutM重組蛋白
  • 貨號：
    CSB-EP518472BRJ-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    枯草芽孢桿菌mutM重組蛋白
  • 貨號：
    CSB-BP518472BRJ
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    枯草芽孢桿菌mutM重組蛋白
  • 貨號：
    CSB-MP518472BRJ
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    mutM
  • Uniprot No.：
  • 別名：
    mutM; fpg; ytaE; BSU29080Formamidopyrimidine-DNA glycosylase; Fapy-DNA glycosylase; EC 3.2.2.23; DNA-(apurinic or apyrimidinic site) lyase MutM; AP lyase MutM; EC 4.2.99.18
  • 種屬：
    Bacillus subtilis (strain 168)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-276
  • 氨基酸序列
    PELPEVETV RRTLTGLVKG KTIKSVEIRW PNIIKRPAEP EEFARKLAGE TIQSIGRRGK FLLFHLDHYV MVSHLRMEGK YGLHQAEEPD DKHVHVIFTM TDGTQLRYRD VRKFGTMHLF KPGEEAGELP LSQLGPEPDA EEFTSAYLKD RLAKTNRAVK TALLDQKTVV GLGNIYVDEA LFRAGVHPET KANQLSDKTI KTLHAEIKNT LQEAIDAGGS TVRSYINSQG EIGMFQLQHF VYGKKDEPCK NCGTMISKIV VGGRGTHFCA KCQTKK
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A.T to G.C transversions. Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 8-oxo-dGTP. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base.
  • 基因功能參考文獻：
    1. MutM promotes mutagenesis that allows nutritionally stressed B. subtilis cells to escape from growth-limiting conditions. PMID: 25825434
  • 蛋白家族：
    FPG family
  • 數據庫鏈接：


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