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  4. Recombinant Arabidopsis thaliana Nuclear cap-binding protein subunit 1 (ABH1), partial

Recombinant Arabidopsis thaliana Nuclear cap-binding protein subunit 1 (ABH1), partial

  • 中文名稱：
    Recombinant Arabidopsis thaliana Nuclear cap-binding protein subunit 1(ABH1) ,partial
  • 貨號：
    CSB-YP882871DOA
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Arabidopsis thaliana Nuclear cap-binding protein subunit 1(ABH1) ,partial
  • 貨號：
    CSB-EP882871DOA
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Arabidopsis thaliana Nuclear cap-binding protein subunit 1(ABH1) ,partial
  • 貨號：
    CSB-EP882871DOA-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Arabidopsis thaliana Nuclear cap-binding protein subunit 1(ABH1) ,partial
  • 貨號：
    CSB-BP882871DOA
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Arabidopsis thaliana Nuclear cap-binding protein subunit 1(ABH1) ,partial
  • 貨號：
    CSB-MP882871DOA
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ABH1
  • Uniprot No.：
  • 別名：
    ABH1; CBP80; ENS; At2g13540; T10F5.8; Nuclear cap-binding protein subunit 1; 80 kDa nuclear cap-binding protein; AtCBP80; NCBP 80 kDa subunit; Abscisic acid-hypersensitive protein 1; ABA-hypersensitive protein 1; Protein ENSALADA
  • 種屬：
    Arabidopsis thaliana (Mouse-ear cress)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing. In the CBC complex, ABH1/CBP80 does not bind directly capped RNAs (m7GpppG-capped RNA) but is required to stabilize the movement of the N-terminal loop of CBP20 and lock the CBC into a high affinity cap-binding state with the cap structure. Involved in flowering regulation, possibly by regulating pre-mRNA splicing of FLC gene. Acts as a negative regulator of abscisic acid signaling in guard cells.
  • 基因功能參考文獻：
    1. the identification of new genes involved in ABA-dependent abiotic stresses using Arabidopsis suppressor mutants of abh1 hypersensitivity to ABA during seed germination. PMID: 23807502
    2. Data suggest that CBP20 and CBP80 (ABH1) have synergistic roles during the salt stress response. PMID: 24689873
    3. SERRATE, CAP BINDING PROTEIN20 (CBP20), and CBP80 are regulators of lincRNA expression and biogenesis. RT-PCR experiments confirmed these three proteins are also needed for splicing of a small group of intron-containing lincRNAs. PMID: 23136377
    4. This intron suppression of transgene silencing requires efficient intron splicing and is dependent on ABH1. PMID: 21689169
    5. ABH1 (CBP80) encodes a large subunit of CBC (CAP BINDING COMPLEX) and the abh1 mutant is drought-tolerant and hypersensitive to ABA during seed germination. PMID: 23196831
    6. The cbp80(abh1) and cbp20/80 mutants had many more changes in alternative splicing in common than did cbp20 and cbp20/80 suggesting that CBP80 plays a more significant role in alternative splicing than CBP20. PMID: 19864257
    7. Abh1 lesion affects several developmental processes, perhaps because the processing of certain mRNAs. PMID: 15361145
    8. CBP20 and CBP80 function in miRNA biogenesis by binding to pri-miRNA transcripts, and are stabilized by ABA by a post-translational mechanism. PMID: 18829588
    9. AtCBP80 is required for the stability of AtCBP20 in the plant cell. PMID: 19453442

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  • 亞細胞定位：
    Nucleus. Cytoplasm. Note=Predominantly nuclear.
  • 蛋白家族：
    NCBP1 family
  • 組織特異性：
    Expressed in all tissues analyzed, including roots, stems, leaves and flowers.
  • 數據庫鏈接：

    KEGG: ath:AT2G13540

    STRING: 3702.AT2G13540.1

    UniGene: At.25306



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