在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Anthopleura elegantissima Toxin APETx2

  • 中文名稱:
    Recombinant Anthopleura elegantissima Toxin APETx2
  • 貨號:
    CSB-YP351639DNA
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Anthopleura elegantissima Toxin APETx2
  • 貨號:
    CSB-EP351639DNA
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Anthopleura elegantissima Toxin APETx2
  • 貨號:
    CSB-EP351639DNA-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Anthopleura elegantissima Toxin APETx2
  • 貨號:
    CSB-BP351639DNA
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Anthopleura elegantissima Toxin APETx2
  • 貨號:
    CSB-MP351639DNA
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    N/A
  • Uniprot No.:
  • 別名:
    Pi-actitoxin-Ael2b; Pi-AITX-Ael2b; Toxin APETx2
  • 種屬:
    Anthopleura elegantissima (Sea anemone)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-42
  • 氨基酸序列
    GTACSCGNSK GIYWFYRPSC PTDRGYTGSC RYFLGTCCTP AD
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    This toxin potently blocks acid-sensing ion channel ASIC3 homotrimers and heterotrimers containing ASIC3 (composed with isoforms of ASIC1 and ASIC2). It also weakly inhibits potassium channels, and sodium channels. On homomeric ASIC3, this protein shows IC(50)=57-87 nM on rat, 37.3 nM on mouse and 175 nM on human channels. The blockade is rapid and reversible. On heterotrimeric forms, the toxin is less potent (IC(50)=117 nM on rat ASIC2b-ASIC3 channel, 900 nM on rat ASIC1b-ASIC3, and 2 uM on rat ASIC1a-ASIC3). It weakly inhibits Kv3.4/KCNC4 potassium channels (3 uM of the toxin inhibits 38% of Kv3.4 current). It reversibly and voltage-dependently inhibits hKv11.1/KCNH2/ERG1 potassium channels (IC(50)=1.21 uM), inhibiting both peak and tail currents without action on channel inactivation. It weakly inhibits rNav1.2/SCN2A (EC(50)=114 nM), rNav1.6/SCN8A current (17% at 1 uM of the toxin) and Nav1.8/SCN10A (IC(50)=6.6 uM on human channels expressed in oocytes, EC(50)=55 nM on rat channels expressed in oocytes, and 2.6 uM on rat channels in DRG neurons). It may act on sodium channels by binding at site 1 or close by, when the pore is in an open configuration. In vivo, central injection does not induce neurotoxin symptoms in mice even after 24 hours. However, it abolishes acid-induced pain in rats.
  • 亞細胞定位:
    Secreted. Nematocyst.
  • 蛋白家族:
    Sea anemone type 3 (BDS) potassium channel toxin family


主站蜘蛛池模板: 国产免费人成视频在线播放播| 人妻熟女一区二区aⅴ林晓雪| 国产av夜夜欢一区二区三区| 小12萝裸体自慰出白浆| 欧美日韩亚洲国产在线制服| 亚洲乱亚洲乱妇50p| 国产成人精品高清在线观看99| 人人爽人人爽人人片av免费| 天天爽夜夜爽视频精品| 沈阳45老熟女高潮喷水亮点| 欧美牲交a欧美牲交aⅴ免费下载| 满春阁精品a∨在线观看| 精品一区二区三区在线播放视频 | 高潮又爽又无遮挡又免费| 久久综合精品国产一区二区三区无码| 欧美va久久久噜噜噜久久| 国产黄大片在线观看| 黑巨人与欧美精品一区| 久久精品国产一区二区免费| 国产欧美日韩中文久久| 久久精品99国产国产精| 无码精品久久一区二区三区 | 日韩少妇白浆无码系列| 亚洲综合成人av一区在线观看| 6080yyy午夜理论片中无码| 国产精品自在线拍国产| 成人无码α片在线观看不卡| 日本高清色倩视频在线观看| 国产精品无码久久久久成人影院| 女人裸露免费视频无遮挡网站| 亚洲国产精品久久久久秋霞小| 亚洲国产成人精品女人久久久 | 成人免费无遮挡在线播放| 久青草久青草视频在线观看| 国产激情艳情在线看视频| 精品夜夜澡人妻无码av蜜桃| 日本高清www午色夜在线视频| 国产 日韩 中文字幕 制服| 天天做天天摸天天爽天天爱| 亚洲欧美日韩中文播放| 免费观看又色又爽又湿的视频|