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  4. Recombinant Anterior pharynx in excess protein 1 (apx-1), partial

Recombinant Anterior pharynx in excess protein 1 (apx-1), partial

  • 中文名稱：
    Recombinant Anterior pharynx in excess protein 1(apx-1),partial
  • 貨號：
    CSB-YP331383CXY
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Anterior pharynx in excess protein 1(apx-1),partial
  • 貨號：
    CSB-EP331383CXY
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Anterior pharynx in excess protein 1(apx-1),partial
  • 貨號：
    CSB-EP331383CXY-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Anterior pharynx in excess protein 1(apx-1),partial
  • 貨號：
    CSB-BP331383CXY
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Anterior pharynx in excess protein 1(apx-1),partial
  • 貨號：
    CSB-MP331383CXY
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    apx-1
  • Uniprot No.：
  • 別名：
    apx-1; K08D9.3Anterior pharynx in excess protein 1
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Probable ligand for lin-12/Notch and glp-1/Notch receptors and involved in the mediation of Notch signaling. Involved in the lin-12/Notch pathway signaling of cell fate in vulval precursor cells (VPCs), acting redundantly with dsl-1 and lag-2. Contributes to the establishment of the dorsal-ventral axis in early embryos. Involved in the specification of the blastomere cell ABp fate, probably acting as a signal from the P2 blastomere to the glp-1/Notch receptor on ABp and ABa. Probably acts as a signal, from the secondary vulval epithelial cells and the vulval muscle type 1 (vm1) cells, to activate the lin-12/Notch pathway in type 2 vulval muscle (vm2) cells, contributing to formation of the postsynaptic muscle plasma membrane extensions, known as muscle arms. Required for oocyte growth control, acting redundantly with lag-2, perhaps signaling via the glp-1/Notch pathway. Plays a somatic role in ovulation during adulthood, perhaps via lin-12/Notch signaling. Involved in establishing left-right asymmetry during intestinal organogenesis.
  • 基因功能參考文獻：
    1. Depletion of apx-1 causes an endomitotic oocyte phenotype and ovulation defects, which are often accompanied by a delay of spermathecal distal neck closure after oocyte entry, Abnormal oocytes and neck closure defects are seen occasionally when apx-1 activity is reduced in adult animals, suggesting a possible post-developmental role for APX-1 signaling in ovulation. PMID: 29371032
  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein. Nucleus. Cytoplasm.
  • 數據庫鏈接：

    KEGG: cel:CELE_K08D9.3

    STRING: 6239.K08D9.3

    UniGene: Cel.19763



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