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Recombinant Androctonus mauretanicus mauretanicus Potassium channel toxin alpha-KTx 3.1

  • 中文名稱:
    Recombinant Androctonus mauretanicus mauretanicus Potassium channel toxin alpha-KTx 3.1
  • 貨號:
    CSB-YP326486AKB
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Androctonus mauretanicus mauretanicus Potassium channel toxin alpha-KTx 3.1
  • 貨號:
    CSB-EP326486AKB
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Androctonus mauretanicus mauretanicus Potassium channel toxin alpha-KTx 3.1
  • 貨號:
    CSB-EP326486AKB-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Androctonus mauretanicus mauretanicus Potassium channel toxin alpha-KTx 3.1
  • 貨號:
    CSB-BP326486AKB
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Androctonus mauretanicus mauretanicus Potassium channel toxin alpha-KTx 3.1
  • 貨號:
    CSB-MP326486AKB
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    N/A
  • Uniprot No.:
  • 別名:
    Potassium channel toxin alpha-KTx 3.1; Kaliotoxin; KTX; Kaliotoxin-1; KTX-1
  • 種屬:
    Androctonus mauretanicus mauretanicus (Scorpion)
  • 蛋白長度:
    Cytoplasmic domain
  • 表達區域:
    1-38
  • 氨基酸序列
    GVEINVKCSG SPQCLKPCKD AGMRFGKCMN RKCHCTPK
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Potent inhibitor voltage-gated potassium channels Kv1.3/KCNA3 (Kd=0.65 nM) and Kv1.1/KCNA1 (Kd=41 nM). It appears to block channel activity by a simple bimolecular inhibition process. Induces a transient period of fast flickering in the channel openings, followed by an almost complete blockade of the channel. Its binding affinity to rat brain synaptosomes is 5-fold higher than this of KTX-3. Binding of the toxin to the channel is associated with significant structural rearrangements in both molecules. It also shows a weak interaction with nicotinic acetylcholine receptors (nAChR), suggesting it may weakly inhibit it.
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 3 subfamily
  • 組織特異性:
    Expressed by the venom gland.


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