在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Adeno-associated virus 2 Protein Rep78 (Rep78)

In Stock
  • 貨號:
    CSB-EP3989ADB(A4)d8
  • 規格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    Rep78
  • Uniprot No.:
  • 種屬:
    Adeno-associated virus 2 (isolate Srivastava/1982) (AAV-2)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    114.3 kDa
  • 表達區域:
    1-621aa
  • 氨基酸序列
    MPGFYEIVIKVPSDLDGHLPGISDSFVNWVAEKEWELPPDSDMDLNLIEQAPLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDECYIPNYLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLTHVSQTQEQNKENQNPNSDAPVIRSKTSARYMELVGWLVDKGITSEKQWIQEDQASYISFNAASNSRSQIKAALDNAGKIMSLTKTAPDYLVGQQPVEDISSNRIYKILELNGYDPQYAASVFLGWATKKFGKRNTIWLFGPATTGKTNIAEAIAHTVPFYGCVNWTNENFPFNDCVDKMVIWWEEGKMTAKVVESAKAILGGSKVRVDQKCKSSAQIDPTPVIVTSNTNMCAVIDGNSTTFEHQQPLQDRMFKFELTRRLDHDFGKVTKQEVKDFFRWAKDHVVEVEHEFYVKKGGAKKRPAPSDADISEPKRVRESVAQPSTSDAEASINYADRYQNKCSRHVGMNLMLFPCRQCERMNQNSNICFTHGQKDCLECFPVSESQPVSVVKKAYQKLCYIHHIMGKVPDACTACDLVNVDLDDCIFEQ
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal MBP-tagged and C-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plays an essential role in the initiation of viral DNA synthesis. Binds specifically to an inverted terminal repeat element (ITR) on the 3' and 5' ends of the viral DNA, where it cleaves a site specifically to generate a priming site for initiation of the synthesis of a complementary strand. Plays also a role as transcriptional regulator, DNA helicase and as key factors in site-specific integration of the viral genome. Regulates host PKA activity by interacting with host PRKX as a mechanism of interfering with helper virus propagation and promoting its own replication. Inhibits the host cell cycle G1/S, S and G2/M transitions. These arrests may provide essential cellular factors for viral DNA replication.
  • 基因功能參考文獻:
    1. SP100 and Adeno-associated virus 2 Rep78 are both located in the nucleolus, which provides the spatial possibility for their interaction. PMID: 22419217
    2. DNA-binding activity of adeno-associated virus Rep 78 is required for complex formation with herpes simplex virus ICP8. PMID: 22205745
    3. The ATPase activity of Rep68 and Rep78 is stimulated up to 10-fold by DNA containing the target sequence derived from the inverted terminal repeat; nontarget DNA stimulates ATPase activity at 50-fold higher concentrations PMID: 17474716
    4. All five assays (pull-down, coimmunoprecipitation, enzyme-linked immunosorbent assay (ELISA), chemical cross-linking, and ATPase activity) provided evidence consistent with Rep78-E1 interaction. PMID: 18092809
  • 亞細胞定位:
    Host nucleus.
  • 數據庫鏈接:

    KEGG: vg:1489608



主站蜘蛛池模板: 米奇影视第四色| 亚洲 欧美 唯美 国产 伦 综合 | 久久视频在线视频精品| 97熟女毛毛多熟妇人妻aⅴ| 天堂资源最新在线| 久久久无码精品亚洲日韩蜜桃| 国产亚洲中文日本不卡二区| 亚洲精品国产高清在线观看| 国产人妻大战黑人20p| 亚洲成av人综合在线观看| 国产清纯白嫩初高生在线观看 | 精品麻豆丝袜高跟鞋av| 国产放荡对白视频在线观看| √天堂中文官网8在线| 色欲av无码一区二区人妻| 亚洲国产精品日本无码网站| 国语精品自产拍在线观看网站 | 久久久久久人妻精品一区| 人妻色综合网站| 国产乱子伦三级在线播放| 中文人妻av大区中文不卡| 国内精品久久久久久不卡影院| 99re热视频这里只精品| 成人无码潮喷在线观看| 99久久久无码国产精品动漫| 真人做人60分钟啪啪免费看| 蜜柚av久久久久久久| 精品人妻无码一区二区三区性| 国产偷抇久久精品a片69| 免费能直接看黄的视频| 把插八插露脸对白内射| 99精品人妻无码专区在线视频区| 好男人日本社区www| 久久婷婷五月综合色奶水99啪| 香蕉av777xxx色综合一区| 色婷婷久久一区二区三区麻豆 | 中文成人无码精品久久久不卡| 999久久久精品国产消防器材| 日日夜夜撸啊撸| 精品人妻无码一区二区三区抖音 | 亚洲精品高清无码视频|