在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant 5'-AMP-activated protein kinase catalytic subunit alpha-2 (aak-2), partial

Recombinant 5'-AMP-activated protein kinase catalytic subunit alpha-2 (aak-2), partial

  • 中文名稱：
    Recombinant 5'-AMP-activated protein kinase catalytic subunit alpha-2(aak-2) ,partial
  • 貨號：
    CSB-YP839238CXY
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant 5'-AMP-activated protein kinase catalytic subunit alpha-2(aak-2) ,partial
  • 貨號：
    CSB-EP839238CXY
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant 5'-AMP-activated protein kinase catalytic subunit alpha-2(aak-2) ,partial
  • 貨號：
    CSB-EP839238CXY-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant 5'-AMP-activated protein kinase catalytic subunit alpha-2(aak-2) ,partial
  • 貨號：
    CSB-BP839238CXY
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant 5'-AMP-activated protein kinase catalytic subunit alpha-2(aak-2) ,partial
  • 貨號：
    CSB-MP839238CXY
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    aak-2
  • Uniprot No.：
  • 別名：
    aak-2; T01C8.15'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK subunit alpha-2; EC 2.7.11.1
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Acts as a sensor that couples lifespan to information about energy levels and insulin-like signals. Role in motility and response to oxidative stress. Involved in the establishment of germline stem cell (GSC) quiescence during dauer development. Plays a role in axon regrowth after axotomy in PLM neurons. Plays a role in the maintenance of glycogen stores which are necessary for resistance to hyperosmotic stress. Plays a role in the regulation of flp-7 secretion from ASI neurons. Keeps the CREB-regulated transcription coactivator 1 homolog crtc-1 inactive which in turn inhibits flp-7 secretion. Following serotonin signaling, derepresses crtc-1 which stimulates flp-7 secretion and subsequent body fat loss.
  • 基因功能參考文獻：
    1. Knockdown of Indy/CeNAC2 increased life span by 22+/-3 % compared to controls, together with a decrease in whole body fat content by ~50%. Indy/CeNAC2 reduction also increased the activation of the intracellular energy sensor AMPK/aak2. PMID: 26318988
    2. As in elevated serotonin signaling, inactivation of AAK-2 in the ASI neurons caused enhanced secretion of dense core vesicles from these neurons. PMID: 24921650
    3. An essential output of RSKS-1 in axon regrowth is the metabolic sensor AMP kinase, AAK-2. PMID: 24431434
    4. AMPK catalytic subunit aak-2 mutants exhibited elevated pharyngeal pumping even in the absence of exogenous 5-HT. PMID: 22768843
    5. The capacity for an animal to survive long bouts of severe oxygen deprivation is likely dependent on specific subunits of the heterotrimeric protein AMPK and energy stores such as carbohydrates. PMID: 21304820
    6. These results show that aging is controlled by overlapping but distinct pathways and that AMPK/aak-2 represents a node in a network of evolutionarily conserved biochemical pathways that control aging. PMID: 16626391
    7. C. elegans larvae that lack LKB1/AMPK (AMP-activated protein kinase) signalling enter dauer normally, but then rapidly consume their stored energy and prematurely expire following vital organ failure PMID: 19052547
    8. aak-2 is required for life span extension in states of impaired glycolysis and calorie restriction. aak-2 initiates increased mitochondrial respiration and increased oxidative stress/ROS formation to promote mitohormesis. PMID: 17908557

    顯示更多

    收起更多

  • 蛋白家族：
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily
  • 組織特異性：
    Expressed in the pharynx, the ventral cord, neurons including the hermaphrodite-specific neuron, body wall muscles, the vulva, the excretory canal, and weakly in the intestine.
  • 數據庫鏈接：

    KEGG: cel:CELE_T01C8.1

    STRING: 6239.T01C8.1b

    UniGene: Cel.17479



主站蜘蛛池模板： 真人作爱90分钟免费看视频| 无码av不卡免费播放| 国产亚洲精品视觉盛宴| 成人区人妻精品一区二区不卡网站| 日韩成人无码中文字幕| 在线亚洲精品国产一区麻豆| 亚洲国产欧美在线成人app| 性高朝久久久久久久| 国产精品无码久久久久久久久久 | 成人精品免费视频在线观看| 国产精品9999久久久久| 国产无遮挡又黄又爽免费视频| 男女猛烈无遮挡免费视频 | 性生交大片免费看| 国产国语毛片在线看国产| 国产综合有码无码视频在线| 国内精品自线一区二区三区2021| 人妻体内射精一区二区三四| 欧美人与动牲交xxxxbbbb| 精品国产福利一区二区| 亚洲欧洲中文日韩乱码av| 久久不见久久见免费影院| 欧美激情乱人伦| 97精品免费公开在线视频| 国产精品久久久久一区二区三区| 免费国产黄网站在线观看动图| 久久精品免视看国产成人| 国产福利永久在线视频无毒不卡| 国内a∨免费播放| 在线视频夫妻内射| 国产成人精品视频国产| 久久精品国产99国产精2021| 亚洲国产精品成人久久| 国产区精品系列在线观看| 少妇人妻久久无码专区| 小鲜肉自慰网站| 特级做a爰片毛片免费看108 | 印度妓女野外xxww| 香蕉久久人人爽人人爽人人片av| 国产成人精品a视频一区| 青青国产揄拍视频|