在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant 5'-AMP-activated protein kinase catalytic subunit alpha-2 (aak-2), partial

Recombinant 5'-AMP-activated protein kinase catalytic subunit alpha-2 (aak-2), partial

  • 中文名稱：
    Recombinant 5'-AMP-activated protein kinase catalytic subunit alpha-2(aak-2) ,partial
  • 貨號：
    CSB-YP839238CXY
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant 5'-AMP-activated protein kinase catalytic subunit alpha-2(aak-2) ,partial
  • 貨號：
    CSB-EP839238CXY
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant 5'-AMP-activated protein kinase catalytic subunit alpha-2(aak-2) ,partial
  • 貨號：
    CSB-EP839238CXY-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant 5'-AMP-activated protein kinase catalytic subunit alpha-2(aak-2) ,partial
  • 貨號：
    CSB-BP839238CXY
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant 5'-AMP-activated protein kinase catalytic subunit alpha-2(aak-2) ,partial
  • 貨號：
    CSB-MP839238CXY
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    aak-2
  • Uniprot No.：
  • 別名：
    aak-2; T01C8.15'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK subunit alpha-2; EC 2.7.11.1
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Acts as a sensor that couples lifespan to information about energy levels and insulin-like signals. Role in motility and response to oxidative stress. Involved in the establishment of germline stem cell (GSC) quiescence during dauer development. Plays a role in axon regrowth after axotomy in PLM neurons. Plays a role in the maintenance of glycogen stores which are necessary for resistance to hyperosmotic stress. Plays a role in the regulation of flp-7 secretion from ASI neurons. Keeps the CREB-regulated transcription coactivator 1 homolog crtc-1 inactive which in turn inhibits flp-7 secretion. Following serotonin signaling, derepresses crtc-1 which stimulates flp-7 secretion and subsequent body fat loss.
  • 基因功能參考文獻：
    1. Knockdown of Indy/CeNAC2 increased life span by 22+/-3 % compared to controls, together with a decrease in whole body fat content by ~50%. Indy/CeNAC2 reduction also increased the activation of the intracellular energy sensor AMPK/aak2. PMID: 26318988
    2. As in elevated serotonin signaling, inactivation of AAK-2 in the ASI neurons caused enhanced secretion of dense core vesicles from these neurons. PMID: 24921650
    3. An essential output of RSKS-1 in axon regrowth is the metabolic sensor AMP kinase, AAK-2. PMID: 24431434
    4. AMPK catalytic subunit aak-2 mutants exhibited elevated pharyngeal pumping even in the absence of exogenous 5-HT. PMID: 22768843
    5. The capacity for an animal to survive long bouts of severe oxygen deprivation is likely dependent on specific subunits of the heterotrimeric protein AMPK and energy stores such as carbohydrates. PMID: 21304820
    6. These results show that aging is controlled by overlapping but distinct pathways and that AMPK/aak-2 represents a node in a network of evolutionarily conserved biochemical pathways that control aging. PMID: 16626391
    7. C. elegans larvae that lack LKB1/AMPK (AMP-activated protein kinase) signalling enter dauer normally, but then rapidly consume their stored energy and prematurely expire following vital organ failure PMID: 19052547
    8. aak-2 is required for life span extension in states of impaired glycolysis and calorie restriction. aak-2 initiates increased mitochondrial respiration and increased oxidative stress/ROS formation to promote mitohormesis. PMID: 17908557

    顯示更多

    收起更多

  • 蛋白家族：
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily
  • 組織特異性：
    Expressed in the pharynx, the ventral cord, neurons including the hermaphrodite-specific neuron, body wall muscles, the vulva, the excretory canal, and weakly in the intestine.
  • 數據庫鏈接：

    KEGG: cel:CELE_T01C8.1

    STRING: 6239.T01C8.1b

    UniGene: Cel.17479



主站蜘蛛池模板： 精品国产丝袜自在线拍国语| 18禁白丝喷水视频www视频| 一本一道色欲综合网中文字幕| 国产美女自卫慰水免费视频| 成人免费无码视频在线网站| 精品无码一区二区三区av| 97精品久久久久中文字幕| 色欲色香天天天综合无码| 99热这里只有精品国产免费免费| 国产无吗一区二区三区在线欢| 少妇av一区二区三区无码| 国产乱码免费卡1卡二卡3| 无码人妻精品一区二区三区久久| 人妻.中文字幕无码| 久久国产乱子伦免费精品| 久久99精品久久久久久秒播| 国产成人亚洲综合网色欲网| 亚洲人成小说网站色在线观看| 日日碰狠狠躁久久躁| 国产 在线 | 日韩| 一本久道久久综合久久爱| 国产三级在线观看播放| 日本丰满熟妇videos| 伊人久久成综合久久影院| 亚洲中文字幕无码卡通动漫野外 | а√天堂www在线天堂小说| 亚洲综合av色婷婷| 欧美日韩亚洲国产综合乱| 无限看片在线版免费视频大全 | 无码日韩精品一区二区人妻| 边吃奶边添下面好爽| 亚洲色欲在线播放一区| 文中字幕一区二区三区视频播放| 波多野结衣的av一区二区三区 | 日产精品久久久一区二区| 免费的很黄很污的视频| 成人毛片av免费| 精品人妻无码一区二区三区蜜桃一 | 丰满人妻熟妇乱又伦精品app| 人人爽人人爱| 日本簧片在线观看|