SN38 Recombinant Monoclonal Antibody
-
中文名稱:SN38重組抗體
-
貨號:CSB-RA187707I1m
-
規格:¥3000
-
圖片:
-
The Binding Activity of Labetuzumab govitecan (Synonyms: IMMU 130; hMN-14-SN-38) with Anti-SN38 antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Labetuzumab govitecan (Synonyms: IMMU 130; hMN-14-SN-38) at 2 μg/mL can bind Anti-SN38 antibody, the EC50 is 3.326 to 4.721 ng/mL.
-
-
其他:
產品詳情
-
產品描述:SN38 Recombinant Monoclonal Antibody(Code: CSB-RA187707I1m)是一種高特異性抗體,靶向SN38分子(7-ethyl-10-hydroxycamptothecin),該分子是拓撲異構酶I抑制劑伊立替康的活性代謝產物,在腫瘤研究領域被廣泛用于誘導DNA損傷及細胞凋亡機制研究。本抗體通過重組技術制備,經ELISA方法嚴格驗證,在1:5000至1:50000的寬泛稀釋范圍內表現出優異的檢測靈敏度和線性關系,可精準識別天然構象的SN38分子。其高批次穩定性與低交叉反應性設計,適用于定量分析SN38在細胞模型或體外藥理學研究中的分布與作用,例如評估藥物遞送效率、代謝動力學或腫瘤細胞耐藥性機制等實驗場景。推薦應用于ELISA平臺檢測,支持細胞培養上清、裂解液等樣本類型的分析,為抗腫瘤藥物開發及分子毒理學研究提供可靠工具。該產品僅供科研使用,不涉及任何臨床相關用途。
-
基因名:SN38
-
別名:SN38, 7-Ethyl-10-hydroxycamptothecin
-
反應種屬:Human
-
免疫原:SN38-BSA
-
標記方式:Non-conjugated
-
克隆類型:Monoclonal
-
抗體亞型:IgG2a
-
純化方式:Affinity-chromatography
-
克隆號:10G11D5
-
濃度:It differs from different batches. Please contact us to confirm it.
-
保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式:Liquid
-
應用范圍:ELISA
-
推薦稀釋比:
Application Recommended Dilution ELISA 1:5000-1:50000 -
Protocols:
-
儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Most popular with customers
-
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
-