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  4. SAA4 Recombinant Monoclonal Antibody

SAA4 Recombinant Monoclonal Antibody

  • 中文名稱：
    SAA4 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA184835A0HU
  • 規格：
    ￥1320
  • 圖片：
    • Immunofluorescence staining of HepG2 cell with CSB-RA184835A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
    • Overlay Peak curve showing HepG2 cells stained with CSB-RA184835A0HU (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100 for?10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 35min at 4℃.Control antibody (green line) was Rabbit IgG (1ug/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SAA4
  • 別名：
    Serum amyloid A-4 protein (Constitutively expressed serum amyloid A protein) (C-SAA), SAA4, CSAA
  • 反應種屬：
    Human
  • 免疫原：
    A synthesized peptide from human SAA4 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    8C2
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IF, FC
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
    FC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Major acute phase reactant.
  • 基因功能參考文獻：
    1. Data identified SAA4 as a protein that was positively correlated with RF and RA. SAA4 may represent a novel prescreening marker for the diagnosis of RA. PMID: 28505104
    2. expressed in invasive trophoblast cells PMID: 24951172
    3. Six apolipoproteins (APOA1, APOA2, APOB, APOC2, APOC3, and APOE) were able to differentiate bladder cancer from hernia. SAA4 was significantly increased in bladder cancer subgroups, whereas ProEGF was significantly decreased in bladder cancer subgroups. PMID: 23631828
    4. studies provide the first evidence for a novel type of AA amyloidosis in which the fibrils were formed from a mutated SAA4 protein PMID: 20536400
    5. The sequences of 1478 and 1836 bp of the SAA1 and SAA4 5'-flanking regions were determined. PMID: 12410800

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  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    SAA family
  • 組織特異性：
    Expressed by the liver; secreted in plasma.
  • 數據庫鏈接：

    HGNC: 10516

    OMIM: 104752

    KEGG: hsa:6291

    STRING: 9606.ENSP00000278222

    UniGene: Hs.1955



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