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  4. PSMB10 Recombinant Monoclonal Antibody

PSMB10 Recombinant Monoclonal Antibody

  • 中文名稱：
    PSMB10 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA912744A0HU
  • 規格：
    ￥1320
  • 圖片：
    • Flow cytometric analysis of PSMB10 expression in HAP-1 cells using PSMB10 antibody. Green, isotype control; red, PSMB10.
    • Immunocytochemical staining of H9c2 cells with PSMB10 antibody. Nuclei were stained blue with DAPI; PSMB10 was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm.
    • Western blotting analysis using PSMB10 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with PSMB10 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    PSMB10
  • 別名：
    PSMB10; Proteasome 20S Subunit Beta 10; LMP10; MECL1; Proteasome (Prosome, Macropain) Subunit, Beta Type, 10; Multicatalytic Endopeptidase Complex Subunit MECl-1; Proteasome Subunit Beta Type-10; Low Molecular Mass Protein 10; Proteasome Subunit Beta 10; Proteasome Subunit Beta-2i; Macropain Subunit MECl-1; Proteasome MECl-1; EC 3.4.25.1; MGC1665; Beta2i; Proteasome Catalytic Subunit 2i; Proteasome Subunit Beta 7i; Proteasome Subunit Beta2i; Proteasome Subunit MECL1; Proteasome Subunit Β2i; PRAAS5; BETA2I
  • 反應種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human PSMB10 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    16H2
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, FC, ICC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    FC 1:200-1:2000
    ICC 1:100-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.
  • 基因功能參考文獻：
    1. this study provided novel evidence demonstrating that LMP10 is a positive regulator of NF-kB signaling, which contributes to Ang II-induced retinopathy. PMID: 29499566
    2. LMP10 nuclear expression in the Human Papillomavirus (HPV)-positive group and LMP10 cytoplasmic expression in the HPV-negative group of patients correlated to better clinical outcome. PMID: 24752327
    3. Adenovirus E1A causes down-regulation of MECL1 expression PMID: 22018786
    4. Multicatalytic endopeptidase complex subunit is involved in antigen presentation and is an important candidate gene for initial exploration of relationships between antigen processing genes and disease resistance. PMID: 17541830
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Peptidase T1B family
  • 數據庫鏈接：

    HGNC: 9538

    OMIM: 176847

    KEGG: hsa:5699

    STRING: 9606.ENSP00000351314

    UniGene: Hs.9661



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