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  4. NDUFB8 Recombinant Monoclonal Antibody

NDUFB8 Recombinant Monoclonal Antibody

  • 中文名稱：
    NDUFB8 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA985048A0HU
  • 規(guī)格：
    ￥1320
  • 圖片：
    • Western Blot
      Positive WB detected in: HEK293 whole cell lysate(30μg), LO2 whole cell lysate(30μg), A431 whole cell lysate(30μg), PC-3 whole cell lysate(30μg), Hela whole cell lysate(30μg), JURKAT whole cell lysate(30μg), A549 whole cell lysate(30μg), Mouse brain tissue lysate(30μg), Mouse heart tissue lysate(30μg)
      All lanes: NDUFB8 antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/40000 dilution
      Predicted band size: 22 kDa
      Observed band size: 19 kDa
      Exposure time：20s
    • IHC image of CSB-RA985048A0HU diluted at 1:100 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
    • IHC image of CSB-RA985048A0HU diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    ASHI antibody; CI-ASHI antibody; Complex I ASHI subunit antibody; Complex I-ASHI antibody; mitochondrial antibody; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8 19kDa antibody; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8 antibody; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8 mitochondrial antibody; NADH-ubiquinone oxidoreductase ASHI subunit antibody; NDUB8_HUMAN antibody; NDUFB8 antibody
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    A synthesized peptide derived from human NDUFB8
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    8B11
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
  • 基因功能參考文獻：
    1. NDUFB8 is a relevant gene in childhood-onset mitochondrial disease. PMID: 29429571
    2. Results describe PTEN and NDUFB8 aberrations in cervical cancer tissue. PMID: 17727244
  • 亞細胞定位：
    Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
  • 蛋白家族：
    Complex I NDUFB8 subunit family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 7703

    OMIM: 602140

    KEGG: hsa:4714

    STRING: 9606.ENSP00000299166

    UniGene: Hs.523215



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