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NAPA Recombinant Monoclonal Antibody

  • 中文名稱:
    NAPA Recombinant Monoclonal Antibody
  • 貨號:
    CSB-RA441466A0HU
  • 規格:
    ¥1320
  • 圖片:
    • IHC image of CSB-RA441466A0HU diluted at 1:100 and staining in paraffin-embedded human colorectal cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    Alpha soluble NSF attachment protein antibody; Alpha-soluble NSF attachment protein antibody; N ethylmaleimide sensitive factor attachment protein alpha antibody; N-ethylmaleimide-sensitive factor attachment protein alpha antibody; napA antibody; NSF attachment protein alpha antibody; SNAA_HUMAN antibody; SNAP alpha antibody; SNAP-alpha antibody; SNAPA antibody
  • 反應種屬:
    Human
  • 免疫原:
    A synthesized peptide from human NAPA protein
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Monoclonal
  • 抗體亞型:
    Rabbit IgG
  • 純化方式:
    Affinity-chromatography
  • 克隆號:
    7F4
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (Probable). Together with GNA12 promotes CDH5 localization to plasma membrane.
  • 基因功能參考文獻:
    1. alphaSNAP is mainly expressed in the neuron brain tissue of patients with temporal lobe epilepsy. Its blood levels were significantly lower in these patients. alphaSNAP levels may increase epilepsy susceptibility. PMID: 26156199
    2. data implicates beta1 integrin, FAK, and paxillin in mediating the observed pro-adhesive effects of alphaSNAP. These results reveal novel roles for alphaSNAP in regulating ECM adhesion and motility of epithelial cells. PMID: 24311785
    3. Study revealed a novel role for alphaSNAP as a negative regulator of autophagy that acts by enhancing mTOR signaling and regulating the integrity of the Golgi complex. PMID: 23187805
    4. novel roles for alphaSNAP in promoting the formation of epithelial adherens junctions and tight junctions by controlling golgi-dependent expression and trafficking of junctional proteins. PMID: 22485163
    5. The most N-terminal part of BKV agnoprotein is involved in the interaction with alpha-SNAP PMID: 21931730
    6. a novel role for alphaSNAP in promoting epithelial cell survival by unique mechanisms involving regulation of Bcl-2 expression and Golgi biogenesis PMID: 22194596
    7. alpha-SNAP plays a key role in the acrosome reaction. PMID: 15542541
    8. G alpha12 interaction with alphaSNAP induces VE-cadherin localization at endothelial junctions and regulates barrier function PMID: 15980433

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  • 亞細胞定位:
    Cell membrane; Peripheral membrane protein.
  • 蛋白家族:
    SNAP family
  • 數據庫鏈接:

    HGNC: 7641

    OMIM: 603215

    KEGG: hsa:8775

    STRING: 9606.ENSP00000263354

    UniGene: Hs.126938



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