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  4. MYO19 Recombinant Monoclonal Antibody

MYO19 Recombinant Monoclonal Antibody

  • 中文名稱：
    MYO19 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA152278A0HU
  • 規(guī)格：
    ￥1320
  • 圖片：
    • Flow cytometric analysis of Myosin XIX expression in HepG2 cells using Myosin XIX antibody. Green, isotype control; red, Myosin XIX.
    • Immunocytochemical staining of HepG2 cells with myosin XIX antibody. Nuclei were stained blue with DAPI; Myosin XIX was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
    • Western blotting analysis using myosin XIX antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with myosin XIX antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    MYO19
  • 別名：
    MYO19; Myosin XIX; MYOHD1; Myosin Head Domain-Containing Protein 1; Myosin Head Domain Containing 1; Unconventional Myosin-XIX; FLJ22865
  • 反應(yīng)種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human MYO19 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    12D1
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, FC, ICC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    FC 1:200-1:2000
    ICC 1:100-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Actin-based motor molecule with ATPase activity that localizes to the mitochondrion outer membrane. Motor protein that moves towards the plus-end of actin filaments. Required for mitochondrial inheritance during mitosis. May be involved in mitochondrial transport or positioning.
  • 基因功能參考文獻(xiàn)：
    1. these data indicate that the MyMOMA domain contains strong membrane-binding activity, and membrane targeting is mediated by a specific, basic region of the MYO19 tail with slow dissociation kinetics appropriate for its role(s) in mitochondrial network dynamics PMID: 27126804
    2. Myo19 is a stably attached OMM molecular motor. PMID: 26659663
    3. Myo19 is a novel regulator of cell division. PMID: 25447992
    4. These results suggest that this novel myosin functions as an actin-based motor for mitochondrial movement in vertebrate cells. PMID: 19932026
  • 亞細(xì)胞定位：
    Mitochondrion outer membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    TRAFAC class myosin-kinesin ATPase superfamily, Myosin family
  • 組織特異性：
    Widely expressed in multiple tissues and cell lines.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 26234

    OMIM: 617379

    KEGG: hsa:80179

    STRING: 9606.ENSP00000409936

    UniGene: Hs.302051



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