MMAE&MMAF Recombinant Monoclonal Antibody
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中文名稱:MMAE&MMAF重組抗體
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貨號:CSB-RA903890I1m
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規格:¥3000
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圖片:
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The Binding Activity of Disitamab vedotin (Synonyms: RC48) with Anti-MMAE&MMAF antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Disitamab vedotin (Synonyms: RC48) at 2 μg/mL can bind Anti-MMAE&MMAF antibody, the EC50 is 3.523 to 5.356 ng/mL. -
The Binding Activity of Depatuxizumab mafodotin (Synonyms: ABT-414) with Anti-MMAE&MMAF antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Depatuxizumab mafodotin (Synonyms: ABT-414) at 2 μg/mL can bind Anti-MMAE&MMAF antibody, the EC50 is 3.022 to 4.198 ng/mL. -
The Binding Activity of Disitamab vedotin (Synonyms: RC48) and Depatuxizumab mafodotin (Synonyms: ABT-414) with Anti-MMAE&MMAF antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Disitamab vedotin (Synonyms: RC48) and Depatuxizumab mafodotin (Synonyms: ABT-414) at 2 μg/mL can bind Anti-MMAE&MMAF antibody, the EC50 is 3.523 to 5.356 ng/mL and 3.022 to 4.198 ng/mL, respectively. -
The purity of MMAE&MMAF was greater than 95% as determined by SEC-HPLC
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其他:
產品詳情
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產品描述:MMAE&MMAF重組單克隆抗體是針對抗體藥物偶聯物(ADC)中關鍵細胞毒性成分開發的檢測工具,適用于酶聯免疫吸附實驗(ELISA)平臺。該抗體特異性識別單甲基奧瑞他汀E(MMAE)和單甲基奧瑞他汀F(MMAF)兩種微管聚合抑制劑,這兩種小分子化合物通過破壞微管網絡抑制細胞分裂,廣泛應用于靶向抗癌藥物的開發。經嚴格驗證,該抗體在1:5000至1:50000的寬泛稀釋范圍內保持穩定檢測性能,具備高靈敏度和低交叉反應特性,可精準檢測復雜生物樣本中MMAE/MMAF的微量存在。其應用場景涵蓋ADC藥物的體外效價評估、藥物偶聯效率分析以及藥代動力學研究等領域,為科研人員提供可靠的定量檢測方案,特別適用于藥物開發過程中關鍵質量屬性的監控及作用機制研究,是生物制藥領域基礎研究的重要工具。
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基因名:MMAE; MMAF
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別名:MMAE, Monomethyl auristatin E, SGD-1010, Vedotin; MMAF, Monomethylauristatin F
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反應種屬:Human
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免疫原:MMAE-BSA
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標記方式:Non-conjugated
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克隆類型:Monoclonal
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抗體亞型:IgG2b
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純化方式:Affinity-chromatography
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克隆號:25G12B5
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式:Liquid
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應用范圍:ELISA
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推薦稀釋比:
Application Recommended Dilution ELISA 1:5000-1:50000 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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